Gene–environment interplay in depressive symptoms: Moderation by age, sex, and physical illness
BackgroundNumerous factors influence late-life depressive symptoms in adults, many not
thoroughly characterized. We addressed whether genetic and environmental influences on …
thoroughly characterized. We addressed whether genetic and environmental influences on …
Genetic heterogeneity in depressive symptoms following the death of a spouse: Polygenic score analysis of the US Health and Retirement Study
Objective: Experience of stressful life events is associated with risk of depression. Yet many
exposed individuals do not become depressed. A controversial hypothesis is that genetic …
exposed individuals do not become depressed. A controversial hypothesis is that genetic …
Assessment of genetic and nongenetic interactions for the prediction of depressive symptomatology: an analysis of the Wisconsin Longitudinal Study using machine …
Objectives. We examined depression within a multidimensional framework consisting of
genetic, environmental, and sociobehavioral factors and, using machine learning …
genetic, environmental, and sociobehavioral factors and, using machine learning …
[HTML][HTML] Unraveling the genetic and environmental relationship between well-being and depressive symptoms throughout the lifespan
BML Baselmans, YE Willems… - Frontiers in …, 2018 - frontiersin.org
Whether well-being and depressive symptoms can be considered as two sides of the same
coin is widely debated. The aim of this study was to gain insight into the etiology of the …
coin is widely debated. The aim of this study was to gain insight into the etiology of the …
Genetic liability for depression, social factors and their interaction effect in depressive symptoms and depression over time in older adults
N Stringa, Y Milaneschi, NM van Schoor… - The American Journal of …, 2020 - Elsevier
Objectives The objectives of this study were to investigate the effect of genetic and social
factors on depressive symptoms and depression over time and to test whether social factors …
factors on depressive symptoms and depression over time and to test whether social factors …
Polygenic risk and social support in predicting depression under stress
Objective: Despite substantial progress in identifying genomic variation associated with
major depression, the mechanisms by which genomic and environmental factors jointly …
major depression, the mechanisms by which genomic and environmental factors jointly …
Nature and nurture: genetic influences and gene-environment interactions in depression
S Benjamin, WD Taylor - Current Psychiatry Reviews, 2010 - ingentaconnect.com
There is a vast literature on the genetic basis for Major Depressive Disorder, a topic which
only continues to expand. Several genes have been examined in the context of MDD. Some …
only continues to expand. Several genes have been examined in the context of MDD. Some …
Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis
Background. Previous studies suggest that the relationship between genetic risk and
depression may be moderated by stressful life events (SLEs). The goal of this study was to …
depression may be moderated by stressful life events (SLEs). The goal of this study was to …
Gene—environment interactions in major depressive disorder
Family, twin, and epidemiologic studies have suggested that both genes and environment
are important risk factors for the development of major depressive disorder (MDD). In the …
are important risk factors for the development of major depressive disorder (MDD). In the …
Genome‐wide association study (GWAS) and genome‐wide by environment interaction study (GWEIS) of depressive symptoms in African American and Hispanic …
EC Dunn, A Wiste, F Radmanesh… - Depression and …, 2016 - Wiley Online Library
Background Genome‐wide association studies (GWAS) have made little progress in
identifying variants linked to depression. We hypothesized that examining depressive …
identifying variants linked to depression. We hypothesized that examining depressive …
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