A family of 25 G protein–coupled receptors, TAS2Rs, mediates bitter taste in humans. Many
of the members of this family are coexpressed in a subpopulation of taste receptor cells on …

A family of approximately 30 TAS2R bitter taste receptors has been identified in mammals.
Their genes evolved through adaptive diversification and are linked to chromosomal loci …

Background In humans, bitterness perception is mediated by~ 25 bitter taste receptors
present in the oral cavity. Among these receptors three, TAS2R10, TAS2R14 and TAS2R46 …

An important question in taste research is how 25 receptors of the human TAS2R family
detect thousands of structurally diverse compounds. An answer to this question may arise …

Bitter taste is a basic taste modality, required to safeguard animals against consuming toxic
substances. Bitter compounds are recognized by G-protein-coupled bitter taste receptors …

The early molecular events in the perception of bitter taste start with the binding of specific
water-soluble molecules to G protein-coupled receptors (GPCRs) encoded by the Tas2r …

The finely tuned bitter taste sensing in humans is orchestrated by a group of 25 bitter taste
receptors (TAS 2Rs), which belong to the G‐protein‐coupled receptor superfamily. TAS 2Rs …

Humans perceive thousands of compounds as bitter. In sharp contrast, only∼ 25 taste 2
receptors (TAS2R) bitter taste receptors have been identified, raising the question as to how …

Bitter taste prevents mammals from ingesting food potentially contaminated with bitter‐
tasting toxins, which are frequent and structurally diverse. It is mediated by a family of …

Sensing potentially harmful bitter substances in the oral cavity is achieved by a group of˜ 25
receptors, named TAS 2Rs, which are expressed in specialized sensory cells and recognize …