Systemic bioavailability from the gastrointestinal tract is reduced with newer inhaled
corticosteroids (ICSs) such as fluticasone, but systemic absorption still occurs via the lung …

Inhaled corticosteroids are being given to more patients, at increasing doses and for longer
periods of time. This has led to renewed concern about side-effects, particularly when higher …

Inhaled corticosteroids (ICS) are common medications, used in respiratory medicine for
controlling conditions such as asthma and other obstructive airway diseases. The systemic …

The National Asthma Education and Prevention Program 1997 guidelines and 2002 update
provide an overview of potential local and systemic side effects associated with inhaled …

The therapeutic ratio for inhaled corticosteroid therapy is determined by the relative dose-
response relationships for anti-asthmatic clinical efficacy and systemic adverse effects. In …

Inhaled corticosteroids (ICSs) are widely used in the treatment of patients with chronic
obstructive pulmonary diseases. However, high-dose regimens and long-term use of ICSs …

Studies of the risk of fracture associated with inhaled corticosteroids are inconclusive and
are limited to short-term effects. We assessed whether long-term use increases this risk. We …

Corticosteroids are adrenal hormones that play important physiologic roles including
modulation of glucose metabolism, protein catabolism, alteration of calcium metabolism …

Objective To appraise the data on systemic adverse effects of inhaled corticosteroids.
Methods A computerized database search from January 1, 1966, through July 31, 1998 …

Inhaled corticosteroids remain the most important therapy for chronic asthma in both adults
and children. As all inhaled corticosteroids act by binding to a common glucocorticoid …