Tear levels of certain cytokines/chemokines can potentially serve as biomarkers for dry eye
and other ocular surface diseases if they remain stable from day-to-day in healthy eyes. The …

An accurate clinical description of the normal patient must be established before the dry eye
patient can be accurately profiled. The current study was designed to (a) determine normal …

Purpose: Tear lysozyme and tear lactoferrin are enzymes synthesized by the lacrimal gland.
Their concentration in human tears reflects tear gland function. Tear gland dysfunction can …

Tear fluids are a mixture of secretions derived from lacrimal glands, accessory lacrimal
glands, conjunctiva, and meibomian glands. Compositional changes to tears occur in the …

Purpose.: Previous studies demonstrated alterations in the tear proteome of dry eye patients.
The aim of the present study was to analyze tear protein patterns of dry eye patients …

The purpose of this study was to analyze inflammation-and pain-related molecules in tears
of patients suffering from chronic ocular pain associated with dry eye (DE) and/or a previous …

Purpose: To investigate the expression of mucin and inflammatory factors in the conjunctival
epithelium of subjects with dry eye and determine a correlation between clinical laboratory …

In the diagnostic process of dry eye disease, the detection of inflammatory activity is critical
in order to evaluate the risk of progression and immunologic shift of the disease, to predict …

Purpose.: To identify the tear proteins associated with the long-term use of glaucoma
medication by using proteomic analysis and to compare these proteins to those previously …

We reviewed the literature for different diagnostic approaches for dry eye disease (DED)
including the most recent advances, contradictions and promising diagnostic tools and …