Biochemical and molecular basis of toxicity

LD Lehman-McKeeman - Haschek and Rousseaux's Handbook of …, 2013 - Elsevier
Pathologists can play a critical role in determining toxic mechanisms because the gross and
microscopic presentation of lesions provides early clues to toxicity. Additionally, the dose …

[图书][B] Principles of biochemical toxicology

JA Timbrell - 2008 - taylorfrancis.com
This leading textbook in the field examines the mechanisms underlying toxicity, particularly
the events at the molecular level and the factors that determine and affect toxicity. The new …

[图书][B] Molecular and biochemical toxicology

RC Smart, E Hodgson - 2013 - books.google.com
An essential resource for graduate students, academic and industrial toxicologists, and
environmental health scientists and professionals Over the course of thirty years and three …

History and basic concepts of toxicology

CN Pope, D Schlenk, FJ Baud - An Introduction to Interdisciplinary …, 2020 - Elsevier
Toxicology is the study of adverse effects of chemical substances on living organisms. The
Society of Toxicology more broadly defined toxicology as “the study of adverse effects of …

Understanding mechanisms of toxicity: insights from drug discovery research

KA Houck, RJ Kavlock - Toxicology and applied pharmacology, 2008 - Elsevier
Toxicology continues to rely heavily on use of animal testing for prediction of potential for
toxicity in humans. Where mechanisms of toxicity have been elucidated, for example …

[图书][B] Mechanistic toxicology: the molecular basis of how chemicals disrupt biological targets

UA Boelsterli - 2002 - taylorfrancis.com
Reductionism to cellular and molecular mechanisms is one of the cornerstones of modern
toxicology, forming the basis for a better understanding of individual toxic effects, and …

[HTML][HTML] New future of cell biology and toxicology: thinking deeper

J Gu, X Wang - Cell Biology and Toxicology, 2016 - Springer
The combination of cell biology and toxicology (CBTo) demonstrates the potential effects of
elements in cellular structures, organelles, functioning properties, metabolic circles …

The future of regulatory toxicology: impact of the biotechnology revolution

JT MacGregor - Toxicological Sciences, 2003 - academic.oup.com
The molecular biology revolution and the advent of genomic and proteomic technologies are
facilitating rapid advances in our understanding of the molecular details of cell and tissue …

Introductory Chapter: Cytotoxicity

TA Çelik - Chapter, 2018 - books.google.com
Cell cytotoxicity refers to the ability of certain chemicals or mediator cells to destroy living
cells. The cytotoxicity is a very important aspect, as destruction of healthy living cells around …

[HTML][HTML] Application to the Study of Mechanisms of Action

… Council (US) Committee on Applications of … - … Toxicology and Risk …, 2007 - ncbi.nlm.nih.gov
The study of biologic mechanisms is a priority for basic and clinical researchers interested in
elucidating the cellular, biochemical, and molecular basis of chemical and drug toxicity …