Alkaloids from marine invertebrates as important leads for anticancer drugs discovery and development

C Imperatore, A Aiello, F D'Aniello, M Senese… - Molecules, 2014 - mdpi.com
The present review describes research on novel natural antitumor alkaloids isolated from
marine invertebrates. The structure, origin, and confirmed cytotoxic activity of more than 130 …

Alkaloids: a source of anticancer agents from nature

AP Gupta, P Pandotra, M Kushwaha, S Khan… - Studies in natural …, 2015 - Elsevier
All types of cancers involve malfunction of genes that control cell growth and characterized
by uncontrolled growth and spread of abnormal cells. Among them, only about 5% of all …

Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other …

W Gul, MT Hamann - Life sciences, 2005 - Elsevier
The marine environment produces natural products from a variety of structural classes
exhibiting activity against numerous disease targets. Historically marine natural products …

Bioactive marine alkaloids

S Urban, SJH Hickford, JW Blunt… - Current organic …, 2000 - ingentaconnect.com
The structures, origins, biogenesis, synthesis and bioactivity of a selection of N-heterocyclic
marine alkaloids are reviewed. The emphasis is on compounds poised as potential …

Novel antitumor agents: marine sponge alkaloids, their synthetic analogs and derivatives

VM Dembitsky, TA Gloriozova… - Mini reviews in …, 2005 - ingentaconnect.com
Present review describes research on novel natural antitumor agents isolated from marine
sponges. More than 90 novel cytotoxic antitumor compounds and their synthetic analogs …

Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers

F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
Cancer is the leading cause of mortality all over the world. Scientific investigation has
demonstrated that disruptions in the process of autophagy are frequently interrelated with …

Bis and tris indole alkaloids from marine organisms: new leads for drug discovery

L Gupta, A Talwar… - Current medicinal …, 2007 - ingentaconnect.com
The marine organisms are a rich source of varied natural products with unique functionality.
Marine natural products chemistry has undergone an explosive growth during the past three …

Polycyclic amine alkaloids (3-alkylpiperidine alkaloids)–novel marine bioactive compounds: structure, synthesis and biochemical aspects

J Rodriguez - Studies in Natural Products Chemistry, 2000 - Elsevier
Marine sponges have frequently afforded a wide variety of alkaloids. Polycyclic amines (3-
alkylpiperidine alkaloids) are secondary metabolites that are profusely found in Indo-Pacific …

Analogues of marine pyrroloiminoquinone alkaloids: synthesis and antitumor properties.

E Delfourne - Anti-Cancer Agents in Medicinal Chemistry, 2008 - europepmc.org
Marine organisms provide a valuable source for natural products. In recent years,
iminoquinone alkaloids including makaluvamines, isobatzellines, tsitsikammamines and …

Marine alkaloids

C Christophersen - The Alkaloids: Chemistry and Pharmacology, 1985 - Elsevier
Publisher Summary This chapter describes guanidine alkaloids, indole alkaloids, pyrrole
alkaloids, and miscellaneous alkaloids. Tetrodotoxin and saxitoxin of this group of alkaloids …