Recombinant human A2B adenosine receptors (A2BARs) and receptors extended on the
amino terminus with hexahistidine and the FLAG epitope, DYKDDDDK (H/F-A2B) were …

The lack of a radiolabeled selective A3 adenosine receptor antagonist is a major drawback
for an adequate characterization of this receptor subtype. This paper describes the …

The numerous and widespread effecfs of adenosine provide both WI opportunity for the
development of novel therapeutic agents acting via adenosine receptors and the challenge …

A possible heterogeneity of adenosine A 1 receptors in brain was evaluated by comparing
drug specificity, regional distribution, and temperature influences on 3 H-labeled ligand …

The extensive amino acid sequence conservation among G protein‐coupled receptors has
been exploited to clone new members of this large family by homology screening or by PCR …

Polyclonal antisera were generated against two identical regions of rat and human A1
adenosine receptors using synthetic multiple-antigenic-peptides as immunogens. Western …

A series of new 2-aralkynyl and 2-heteroaralkynyl derivatives of NECA were synthesized
and studied in binding and functional assays to assess their potency for the A2a compared …

1 The present study describes the binding to rat striatal A2A adenosine receptors of the new
potent and selective antagonist radioligand,[3H]‐5‐amino‐7‐(2‐phenylethyl)‐2‐(2‐furyl) …

A three-dimensional model of the human A2A adenosine receptor (AR) and its docked
ligands was built by homology to rhodopsin and validated with site-directed mutagenesis …

Adenosine A1 and A2 receptors have been the subject of intense activity in the
pharmaceutical industry. Adenosine agonists, which are almost exclusively derivatives of …