The ouroboros of autoimmunity

JL Casanova, J Peel, J Donadieu, AL Neehus… - Nature …, 2024 - nature.com
Human autoimmunity against elements conferring protective immunity can be symbolized by
the 'ouroboros', a snake eating its own tail. Underlying infection is autoimmunity against …

Autoimmunity through infection or immunization?

M Regner, PH Lambert - Nature immunology, 2001 - nature.com
Autoimmunity through infection or immunization? | Nature Immunology Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

Monogenic autoimmunity and infectious diseases: The double-edged sword of immune dysregulation

TM Bigley, MA Cooper - Current Opinion in Immunology, 2021 - Elsevier
Highlights•Inborn errors of immunity include monogenic autoimmunity.•Immune
dysregulation in monogenic autoimmunity can alter pathogen defense.•Understanding …

Pathogen infection and autoimmune disease

U Christen - Clinical & Experimental Immunology, 2019 - academic.oup.com
For many readers, the title 'pathogen infection and autoimmune disease'might suggest that
pathogens are the suspected drivers of autoimmune disease. This, of course, is a perfectly …

Infectious diseases, autoantibodies, and autoimmunity

D Johnson, W Jiang - Journal of Autoimmunity, 2023 - Elsevier
Infections are known to trigger flares of autoimmune diseases in humans and serve as an
inciting cause of autoimmunity in animals. Evidence suggests a causative role of infections …

Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?

C Benoist, D Mathis - Nature immunology, 2001 - nature.com
Autoimmune diseases remain one of the mysteries that perplex immunologists. What makes
the immune system, which has evolved to protect an organism from foreign invaders, turn on …

Infections and autoimmunity–friends or foes?

S Kivity, N Agmon-Levin, M Blank, Y Shoenfeld - Trends in immunology, 2009 - cell.com
Autoimmunity can be triggered by many environmental factors, among which infectious
agents are pivotal. Here, we summarize current knowledge of the relationship between …

Pathogen infection and autoimmunity

U Christen - International reviews of immunology, 2014 - Taylor & Francis
Autoimmune diseases are an ever-growing problem for patients as well as for the economy.
It has been estimated that 5–10% of the general population suffer from any kind of …

Antigen-presenting cell activation: a link between infection and autoimmunity?

S Kissler, SM Anderton, DC Wraith - Journal of autoimmunity, 2001 - Elsevier
The onset of autoimmune diseases such as type I diabetes and multiple sclerosis is often
thought to be associated with infection. This has led to studies of molecular mimicry between …

Vaccines and autoimmunity

M De Martino, E Chiappini… - International Journal of …, 2013 - journals.sagepub.com
Vaccines have eradicated or controlled many infectious diseases, saving each year millions
of lives and quality of life of many other millions of people. In spite of the success of vaccines …