For decades, the main question immunologists have asked about autoimmunity is “what
causes a break in self-tolerance?” We have not found good answers to that question, and I …

Introduction: Autoimmunity occurs when the immune system recognizes and attacks host
tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria …

The basic function of the adaptive immune system is to distinguish self from foreign. The
failure of self tolerance can result in autoimmunity, which comes in many forms but still …

Autoimmunity refers to an inappropriate immune response against self-components of the
host that results in pathological conditions. Autoimmune diseases are characterized by an …

In the thymus, most T cells that react avidly with self-peptides in association with MHC
molecules are physically or functionally deleted. However, it is clear that not all potentially …

The genesis of this article is as a follow-up to a presentation delivered at the 2011 American
Association of Naturopathic Physicians (AANP) annual convention on the topic of …

Autoimmune disease: why and where it occurs | Nature Medicine Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Viral infection can induce the production of autoantibodies : Current Opinion in Rheumatology
Viral infection can induce the production of autoantibodies : Current Opinion in Rheumatology …

The core function of the immune system is to protect against infection. As the number of
existing and potential infectious agents is almost limitless, the immune system requires a …

The vast interindividual clinical variability observed in any microbial infection—ranging from
silent infection to lethal disease—is increasingly being explained by human genetic and …