Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …

Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …

Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

Lipids are essential constituents for malignant tumors, as they are absolutely required for
tumor growth and dissemination. Provided by the tumor microenvironment (TME) or by …

With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Dysregulation in lipid metabolism is among the most prominent metabolic alterations in
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …

Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …

Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest
in recent years in such areas as energy sources, cell membrane components, and signaling …

To proliferate, metastasize, or resist stress conditions imposed by the microenvironment,
many cancer cells rely on fatty acid β-oxidation to generate acetyl-CoA and fuel the TCA …

Cancer cells frequently display fundamentally altered cellular metabolism, which provides
the biochemical foundation and directly contributes to tumorigenicity and malignancy …