Cancer cells are often exposed to a metabolically challenging environment with scarce
availability of oxygen and nutrients. This metabolic stress leads to changes in the balance …

Metabolic reprogramming is a central feature of transformed cells. Cancer metabolism is
now fully back in the focus of cancer research, as the interactions between oncogenic …

Many human diseases, including metabolic, immune and central nervous system disorders,
as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their …

Tumour growth and dissemination is largely dependent on nutrient availability. It has
recently emerged that the tumour microenvironment is rich in a diverse array of lipids that …

Tumors undergo metabolic transformations to sustain uncontrolled proliferation, avoid cell
death, and seed in secondary organs. An increased focus on cancer lipid metabolism has …

Alteration of lipid metabolism has been increasingly recognized as a hallmark of cancer
cells. The changes of expression and activity of lipid metabolizing enzymes are directly …

Simple Summary Melanoma is a devastating skin cancer characterized by an impressive
metabolic plasticity. Melanoma cells are able to adapt to the tumor microenvironment by …

One of the most important metabolic hallmarks of cancer cells is deregulation of lipid
metabolism. In addition, enhancing de novo fatty acid (FA) synthesis, increasing lipid uptake …

The disorder of lipid metabolism is pathologically linked to hyperlipidemia, lipid storage
disease, obesity and other related diseases. Intriguingly, recent studies have revealed that …

Metabolic activity of malignant cells is very different from that of their nontransformed
equivalents, which establishes metabolic reprogramming as an important hallmark of every …