Cancer cells display altered cellular lipid metabolism, including disruption in endogenous
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …

Cancer cells undergo metabolic reprogramming to support cell proliferation, growth, and
dissemination. Alterations in lipid metabolism, and specifically the uptake and synthesis of …

Increased lipogenesis is a hallmark of a wide variety of cancers and is under intense
investigation as potential antineoplastic target. Although brisk lipogenesis is observed in the …

Cancer cells are highly dependent on different metabolic pathways for sustaining their
survival, growth, and proliferation. Lipid metabolism not only provides the energetic needs of …

Proteins are often credited as the macromolecule responsible for performing critical cellular
functions, however lipids have recently garnered more attention as our understanding of …

Lipids, as one of the three primary energy sources, provide energy for all cellular life
activities. Lipids are also known to be involved in the formation of cell membranes and play …

Obesity is a leading contributing factor to cancer development worldwide. Epidemiological
evidence suggests that diet affects cancer risk and also substantially alters therapeutic …

Bioactive lipids are essential components of human cells and tissues. As discussed in this
review, the cancer lipidome is diverse and malleable, with the ability to promote or inhibit …

Reprogramming of lipid metabolism has received increasing recognition as a hallmark of
cancer cells because lipid dysregulation and the alteration of related enzyme profiles are …

Fatty acid metabolism is known to support tumorigenesis and disease progression as well
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …