The ability to prospectively identify metastasis-initiating cells is essential for developing new
anti-metastasis therapeutics. In a recent issue of Nature, Pascual et al.(2017) demonstrate …

Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain
uncontrolled proliferation and survive in unfavorable environments that lack oxygen and …

The tumor microenvironment can be hypoxic, acidic, and deficient in nutrients, thus causing
the metabolism of tumor cells as well as the neighboring stromal cells to be remodelled to …

Alterations in lipid metabolism have been reported in many types of cancer. Lipids have
been implicated in the regulation of proliferation, differentiation, apoptosis, inflammation …

Excess adiposity is a risk factor for several cancer types. This is likely due to complex
mechanisms including alterations in the lipid milieu that plays a pivotal role in multiple …

Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …

Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …

Currently, there is renewed interest in elucidating the metabolic characteristics of cancer and
how these characteristics may be exploited as therapeutic targets. Much attention has …

Simple Summary Cancer cells directly control nutrient uptake and utilization in a different
manner from that of normal cells. These metabolic changes drive growth, proliferation of …

Modulation of membrane lipid composition and organization is currently developing as an
effective therapeutic strategy against a wide range of diseases, including cancer. This field …