Isolation, purification and characterization of exosomes from Fibroblast cultures of skeletal muscle

D Van De Vlekkert, X Qiu, I Annunziata, A d'Azzo - Bio-protocol, 2020 - bio-protocol.org
Exosomes are dynamic nanovesicles secreted by virtually all cells and are present in all
biological fluids. Given their highly heterogeneous content exosomes have been implicated …

[HTML][HTML] Biogenesis, biologic function and clinical potential of exosomes in different diseases

A Magdy Beshbishy, S Alghamdi, TGE Onyiche… - Applied Sciences, 2020 - mdpi.com
Exosomes are extracellular vesicles (EVs) belonging to the nanovesicles family that function
as signaling molecules between cells. After their first description in the late 1960s, interest in …

[HTML][HTML] Adipose-secreted exosomes and their pathophysiologic effects on skeletal muscle

B Yue, H Wang, X Cai, J Wang, Z Chai, W Peng… - International Journal of …, 2022 - mdpi.com
Due to its prominent secretory activity, adipose tissue (AT) is now considered a major player
in the crosstalk between organs, especially with skeletal muscle. In which, exosomes are …

Exosomes in inflammation and inflammatory disease

BD Chan, WY Wong, MML Lee, WCS Cho, BK Yee… - …, 2019 - Wiley Online Library
Exosomes are a subset of extracellular vesicles released by all cell types and involved in
local and systemic intercellular communication. In the past decade, research into exosomes …

[HTML][HTML] Harnessing exosomes as cutting-edge drug delivery systems for revolutionary osteoarthritis therapy

J Lu, Y Zhang, X Yang, H Zhao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Exosomes, remarkable extracellular vesicles, have emerged as an advanced frontier in
intercellular communication. This remarkable capacity positions them as promising …

Exosomes: current knowledge and future perspectives

S Singh, D Paul, V Nath - Tissue Barriers, 2024 - Taylor & Francis
Exosomes are membrane-bound micro-vesicles that possess endless therapeutic potential
for treatment of numerous pathologies including autoimmune, cardiovascular, ocular, and …

[HTML][HTML] Effects of exosomes upon the metabolic activities of human osteoarthritic articular cartilage in situ

A Rey-Rico, J Reinecke, P Wehling… - Osteoarthritis and …, 2015 - oarsijournal.com
Purpose: Exosomes are small nanosized extracellular membrane vesicles produced within
multivesicular bodies of the late endocytic compartment of hematopoietic and non …

Disease-microenvironment modulation by bare-or engineered-exosome for rheumatoid arthritis treatment

ES Lee, H Ko, CH Kim, HC Kim, SK Choi… - Biomaterials …, 2023 - spj.science.org
Background Exosomes are extracellular vesicles secreted by eukaryotic cells and have
been extensively studied for their surface markers and internal cargo with unique functions …

[HTML][HTML] Osteoarthritic subchondral bone release exosomes that promote cartilage degeneration

X Wu, R Crawford, Y Xiao, X Mao, I Prasadam - Cells, 2021 - mdpi.com
Altered subchondral bone and articular cartilage interactions have been implicated in the
pathogenesis of osteoarthritis (OA); however, the mechanisms remain unknown. Exosomes …

Potential of exosomes as cell-free therapy in articular cartilage regeneration: A review

CY Ng, JY Chai, JB Foo… - International journal …, 2021 - Taylor & Francis
Abstract Treatment of cartilage defects such as osteoarthritis (OA) and osteochondral defect
(OCD) remains a huge clinical challenge in orthopedics. OA is one of the most common …