Alcohol-related hepatocellular carcinoma (HCC) develops with advanced alcoholic liver
disease and liver fibrosis. Using adult mice, we evaluate the effect of alcoholic …

AIM: To establish a mouse model of alcohol-driven hepatocellular carcinoma (HCC) that
develops in livers with alcoholic liver disease (ALD). METHODS: Adult C57BL/6 male mice …

Chronic alcohol consumption increases the risk of hepatocellular carcinoma (HCC).
However, little is known about the potential immunological mechanisms by which ethanol …

Background Chronic intake of alcohol increases the risk of gastrointestinal and hepatic
carcinogenesis. The present study was focused to investigate the incidence and mechanism …

Liver cancer stem cells (CSCs) are involved in tumorigenesis, progression, drug resistance
and recurrence of hepatocellular carcinoma (HCC). However, the underlying mechanism for …

Persistent inflammation in chronic hepatitis plays a major role in the development of
hepatocellular carcinoma (HCC). In this study, the major inflammatory cytokines expressed …

Background Hepatocellular carcinoma (HCC) is a major global health burden. Although
chronic, heavy alcohol abuse is an established risk factor for HCC, obesity is emerging as …

Alcohol is a well-known risk factor for hepatocellular carcinoma. Autophagy plays a dual role
in liver cancer, as it suppresses tumor initiation and promotes tumor progression …

Background Alcohol consumption promotes hepatocellular carcinoma (HCC). The
responsible mechanisms are not well understood. Hepatocarcinogenesis increases with …

The death rate from hepatocellular carcinoma (HCC) is increasing, and liver cancer is the
second leading cause of cancer‐related mortality worldwide. Most patients with HCC have …