Etoposide (ETO) is a semi-synthetic derivative of podophyllotoxin with a definite antitumour
effect, but its use is hampered by poor solubility and numerous side-effects. In this work, we …

A novel albumin polymer hybrid with a core–shell structure was designed to target delivery
of bufalin, which is an antineoplastic monomer with serious cardiotoxicity. The sheath layer …

The effectiveness of chemotherapeutic agents for hepatocellular carcinoma (HCC) is
unsatisfactory because of tumor heterogeneity, multidrug resistance, and poor target …

Albumin-based hydrogels have emerged as promising nanoparticle systems for the effective
delivery of hydrophobic anticancer drugs. Anti-cancer drugs often cause some adverse …

Metastasis and recurrence are the main causes of death in cancer patients; however, there
are few medicines that can inhibit tumor growth and metastasis at the same time. In this …

Nintedanib (ND) was known as a triple tyrosine kinase inhibitors, inhibiting angiogenesis
and tissue fibrosis. Biguanide group has attracted much attention for its great penetrating …

Albumin-based nanoparticles are widely used to delivery anticancer drug because they
promote the accumulation of drugs in tumor sites. Nanoparticles with surface immobilized …

Triple-negative breast cancers (TNBCs), devoid of hormone receptors and human epidermal
growth-factor receptor-2/Neu expression, bring about poor prognosis and induce a high rate …

Human serum albumin (HSA) has the characteristics of biocompatibility and long circulation,
which is widely used as the carrier of insoluble anticancer drugs, but it also has some …

It was widely accepted that polymeric nanodrugs held superiority in enhancing antitumor
efficacy, reducing side effect and achieving better long-term prognosis. However, there still …