A microfluidic device for efficient chemical testing using Caenorhabditis elegans

P Song, W Zhang, A Sobolevski, K Bernard… - Biomedical …, 2015 - Springer
The nematode worm Caenorhabditis elegans has been employed as a popular model
organism in many fields of biological research. In this paper, we present a microfluidic …

Microfluidic chamber arrays for whole-organism behavior-based chemical screening

K Chung, M Zhan, J Srinivasan, PW Sternberg… - Lab on a Chip, 2011 - pubs.rsc.org
The nematode Caenorhabditis elegans is an important model organism in genetic research
and drug screening because of its relative simplicity, ease of maintenance, amenability to …

[HTML][HTML] Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans

BP Gupta, P Rezai - Micromachines, 2016 - mdpi.com
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies
related to fundamental biological processes, disease modelling, and drug discovery. Due to …

A microfluidic device for automated, high-speed microinjection of Caenorhabditis elegans

P Song, X Dong, X Liu - Biomicrofluidics, 2016 - pubs.aip.org
The nematode worm Caenorhabditis elegans has been widely used as a model organism in
biological studies because of its short and prolific life cycle, relatively simple body structure …

Microfluidic Systems for Whole‐Animal Screening with C. elegans

N Ghorashian, SK Gökçe… - Micro‐and Nanosystems …, 2016 - Wiley Online Library
In this chapter, we discuss the biological relevance of the nematode, Caenorhabditis
elegans (C. elegans) in studying human disease and injury, and how it is amenable to high …

[HTML][HTML] Microfluidic Devices in Advanced Caenorhabditis elegans Research

M Muthaiyan Shanmugam, T Subhra Santra - Molecules, 2016 - mdpi.com
The study of model organisms is very important in view of their potential for application to
human therapeutic uses. One such model organism is the nematode worm, Caenorhabditis …

Recent Advances and Trends in Microfluidic Platforms for C. elegans Biological Assays

F Kamili, H Lu - Annual Review of Analytical Chemistry, 2018 - annualreviews.org
Microfluidics has proven to be a key tool in quantitative biological research. The C. elegans
research community in particular has developed a variety of microfluidic platforms to …

[HTML][HTML] Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans

D Midkiff, A San-Miguel - Molecules, 2019 - mdpi.com
The nematode Caenorhabditis elegans is a powerful model organism that has been widely
used to study molecular biology, cell development, neurobiology, and aging. Despite their …

Analysis of Caenorhabditis elegans in microfluidic devices

H Wen, JH Qin - Science China Chemistry, 2012 - Springer
Caenorhabditis elegans (C. elegans) is widely adopted as a model organism for a variety of
biological studies including development, genetics and neurobiology. Micro-scale …

Microfluidic Platform for the Study of Caenorhabditis elegans

W Shi, H Wen, B Lin, J Qin - Microfluidics: Technologies and Applications, 2011 - Springer
Caenorhabditis elegans is a well-established model organism for the study of various
biological areas. However, the procedures generally used for this worm are limited by the …