PmrAB, a Two-Component Regulatory System of Pseudomonas aeruginosa That Modulates Resistance to Cationic Antimicrobial Peptides and Addition of …
SM Moskowitz, RK Ernst, SI Miller - Journal of bacteriology, 2004 - Am Soc Microbiol
Spontaneous polymyxin-resistant mutants of Pseudomonas aeruginosa were isolated. The
mutations responsible for this phenotype were mapped to a two-component signal …
mutations responsible for this phenotype were mapped to a two-component signal …
Phosphate starvation promotes swarming motility and cytotoxicity of Pseudomonas aeruginosa
M Bains, L Fernández… - Applied and environmental …, 2012 - Am Soc Microbiol
We investigated the transcriptional responses of Pseudomonas aeruginosa under
phosphate-deficient (0.2 mM) conditions compared to phosphate sufficiency (1 mM). This …
phosphate-deficient (0.2 mM) conditions compared to phosphate sufficiency (1 mM). This …
Signal‐specific temporal response by the Salmonella PhoP/PhoQ regulatory system
SY Park, EA Groisman - Molecular microbiology, 2014 - Wiley Online Library
The two‐component system PhoP/PhoQ controls a large number of genes responsible for a
variety of physiological and virulence functions in S almonella enterica serovar …
variety of physiological and virulence functions in S almonella enterica serovar …
Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa
K Barrow, DH Kwon - Antimicrobial agents and chemotherapy, 2009 - Am Soc Microbiol
Polymyxins are often the only option to treat acquired multidrug-resistant Pseudomonas
aeruginosa. Polymyxin susceptibility in P. aeruginosa PAO1 is associated with the …
aeruginosa. Polymyxin susceptibility in P. aeruginosa PAO1 is associated with the …
Crystal Structures of the Receiver Domain of the Response Regulator PhoP from Escherichia coli in the Absence and Presence of the Phosphoryl Analog …
P Bachhawat, AM Stock - Journal of bacteriology, 2007 - Am Soc Microbiol
The response regulator PhoP is part of the PhoQ/PhoP two-component system involved in
responses to depletion of extracellular Mg2+. Here, we report the crystal structures of the …
responses to depletion of extracellular Mg2+. Here, we report the crystal structures of the …
Polymyxin Resistance of Pseudomonas aeruginosa phoQ Mutants Is Dependent on Additional Two-Component Regulatory Systems
AD Gutu, N Sgambati, P Strasbourger… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Pseudomonas aeruginosa can develop resistance to polymyxin as a consequence of
mutations in the PhoPQ regulatory system, mediated by covalent lipid A modification …
mutations in the PhoPQ regulatory system, mediated by covalent lipid A modification …
Extracellular DNA-induced antimicrobial peptide resistance in Salmonella enterica serovar Typhimurium
L Johnson, SR Horsman, L Charron-Mazenod… - BMC microbiology, 2013 - Springer
Abstract Background The Salmonella enterica serovar Typhimurium PhoPQ two component
system (TCS) is activated by low Mg 2+ levels, low pH and by antimicrobial peptides (AP) …
system (TCS) is activated by low Mg 2+ levels, low pH and by antimicrobial peptides (AP) …
Aminoglycoside-Modifying Enzymes Are Sufficient to Make Pseudomonas aeruginosa Clinically Resistant to Key Antibiotics
A Thacharodi, IL Lamont - Antibiotics, 2022 - mdpi.com
Aminoglycosides are widely used to treat infections of Pseudomonas aeruginosa. Genes
encoding aminoglycoside-modifying enzymes (AMEs), acquired by horizontal gene transfer …
encoding aminoglycoside-modifying enzymes (AMEs), acquired by horizontal gene transfer …
PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients
SM Moskowitz, MK Brannon, N Dasgupta… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Pseudomonas aeruginosa can develop resistance to polymyxin and other cationic
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …
A Pseudomonas aeruginosa EF-Hand Protein, EfhP (PA4107), Modulates Stress Responses and Virulence at High Calcium Concentration
SA Sarkisova, SR Lotlikar, M Guragain, R Kubat… - PLoS …, 2014 - journals.plos.org
Pseudomonas aeruginosa is a facultative human pathogen, and a major cause of
nosocomial infections and severe chronic infections in endocarditis and in cystic fibrosis …
nosocomial infections and severe chronic infections in endocarditis and in cystic fibrosis …