Pseudomonas aeruginosa employs numerous, complex regulatory elements to control
expression of its many virulence systems. The P. aeruginosa AlgZR two-component …

Pseudomonas aeruginosa has an extraordinary capacity to evade the activity of antibiotics
through a complex interplay of intrinsic and mutation-driven resistance pathways, which are …

Pseudomonas aeruginosa can develop resistance to polymyxin and other cationic
antimicrobial peptides. Previous work has shown that mutations in the PmrAB and PhoPQ …

Abstract The PmrA–PmrB two‐component system of Salmonella enterica controls resistance
to the peptide antibiotic polymyxin B and to several antimicrobial proteins from human …

Aims: Proton motive force (PMF) inhibition enhances the intracellular accumulation of
autoinducers possibly interfering with biofilm formation. We evaluated the effect of the PMF …

The MexXY components of the MexXY-OprM multidrug efflux system of Pseudomonas
aeruginosa are encoded by a MexZ repressor-regulated operon that is inducible by …

Multidrug-resistant Pseudomonas aeruginosa presents a global medical challenge, and
polymyxins are a key last-resort therapeutic option. Unfortunately, polymyxin resistance in P …

NalC is a TetR type regulator that represses the multidrug efflux pump MexAB–OprM in
Pseudomonas aeruginosa. Here we explain the mechanism of NalC‐mediated regulation of …

While the early stages of biofilm formation have been well characterized, less is known
about the requirements for Pseudomonas aeruginosa to maintain a mature biofilm. We …

Pseudomonas aeruginosa displays intrinsic resistance to many antibiotics and known to
acquire actively genetic mutations for further resistance. In this study, we attempted to …