Nitric oxide and the gut

D Jourd'heuil, MB Grisham, DN Granger - Current gastroenterology …, 1999 - Springer
Nitric oxide (NO) has been implicated as a modulator of blood flow, motility, electrolyte and
water transport, and the function of endothelial cells, platelets, mast cells, and macrophages …

Nitric oxide in the gut.

AL Salzman - New horizons (Baltimore, Md.), 1995 - europepmc.org
Nitric oxide (NO.) plays a central role in the physiology of the gastrointestinal tract and its
response to critical illness. Potential sources of NO. in the gut include: intrinsic intestinal …

Nitric oxide-a mediator of inflammation or mucosal defence

BJR Whittle - European journal of gastroenterology & hepatology, 1997 - journals.lww.com
Nitric oxide (NO) can exert both protective and proinflammatory actions in the
gastrointestinal tract. NO, formed physiologically by constitutive NO synthases, regulates …

Nitric oxide in gastrointestinal health and disease

V Shah, G Lyford, G Gores, G Farrugia - Gastroenterology, 2004 - Elsevier
Nitric oxide is an intracellular and intercellular messenger with important functions in a
number of physiologic and pathobiologic processes within gastroenterology and …

III. A molecular prelude to intestinal inflammation

MJS Miller, M Sandoval - American Journal of Physiology …, 1999 - journals.physiology.org
Nitric oxide (NO) synthesis is markedly augmented in states of inflammation, largely due to
the expression of inducible nitric oxide synthase (iNOS). Although NO has anti-inflammatory …

Nitric oxide and intestinal inflammation

P Kubes, DM McCafferty - The American journal of medicine, 2000 - Elsevier
Inflammation of the intestinal tract remains a very serious concern in the clinical setting.
Unfortunately, to date, the mechanisms underlying many inflammatory conditions such as …

A critical role for nitric oxide in intestinal barrier function and dysfunction

I Alican, P Kubes - American Journal of Physiology …, 1996 - journals.physiology.org
There is growing evidence that endogenous nitric oxide (NO) regulates mucosal barrier
integrity under physiological conditions and counters the increase in mucosal permeability …

I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation

MB Grisham, D Jourd'Heuil… - American Journal of …, 1999 - journals.physiology.org
The role of nitric oxide (NO) in inflammation represents one of the most studied yet
controversial subjects in physiology. A number of reports have demonstrated that NO …

Nitric oxide in the gastrointestinal tract: opportunities for drug development

JL Wallace - British journal of pharmacology, 2019 - Wiley Online Library
Nitric oxide (NO) plays important roles in gastrointestinal mucosal defence, as well as in the
pathogenesis of several gastrointestinal diseases (eg irritable bowel syndrome and …

[HTML][HTML] Role of nitric oxide in gastrointestinal tract

D Rachmilewitz - World Journal of Gastroenterology, 1998 - wjgnet.com
Nitric oxide is a gaseous free radical synthesized via L-arginine oxidation by a family of nitric
oxide syntheses (NOS). Isomeric forms of NOS, representing at least three distinct and …