Depression is a state of low mood and aversion to activity, affecting a person's thoughts,
behavior, motivation, feelings and sense of well-being, which is associated with dramatical …

Background Depression is a common and complex mental disease, and its pathogenesis
involves several brain regions. Abnormalities in the amygdala-hippocampal neural circuits …

Stress causes extensive changes in hippocampal genomic expression, leading to changes
in hippocampal structure and function. The dynamic changes in hippocampal gene …

Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The
pathogenesis of MDD remained unclear, and it may be associated with exposure to different …

Stress refers to physiological or psychological stimuli that disrupt homeostasis and induce
pathophysiological conditions due to maladaptive response, sometimes resulting in mental …

Introduction Major depressive disorder (MDD) is a recurrent, devastating mental disorder,
which affects> 350 million people worldwide, and exerts substantial public health and …

Chronic stress refers to nonspecific systemic reactions under the over-stimulation of different
external and internal factors for a long time. Previous studies confirmed that chronic …

Chronic stress is an essential factor leading to depression. However, there exist individual
differences in people exposed to the same stressful stimuli. Some people display negative …

Major depressive disorder (MDD) is a prevalent, chronic, and relapse‐prone psychiatric
disease. However, the intermediate molecules resulting from stress and neurological …

Data from clinical investigations and laboratory fundings have provided preliminary
evidence for the effectiveness and safety of acupuncture therapy in depression. However …