[PDF][PDF] Localisation and temporal changes in prostaglandin G/H synthase-1 and-2 content in ovine intrauterine tissues in relation to glucocorticoid-induced and …

WJ McLaren, IR Young, GE Rice - Journal of Endocrinology, 2000 - Citeseer
Parturition in the ewe is preceded by an increase in the synthesis of prostaglandins (PGs) by
gestational tissues. To establish the uterine source of these PGs, placental cotyledons, fetal …

Expression of prostaglandin G/H synthase-1 and-2 in ovine amnion and placenta following glucocorticoid-induced labour onset

WJ McLaren, IR Young, MH Wong… - Journal of …, 1996 - joe.bioscientifica.com
Parturition in the sheep is preceded by an increase in the synthesis of prostaglandins by
intrauterine tissues. Prostaglandin G/H synthase (PGHS) is the central enzyme involved in …

Immunohistochemical localization of prostaglandin G/H synthase 1 and 2 in sheep placenta after glucocorticoid-induced and spontaneous labour.

WJ McLaren, IR Young, GE Rice - Journal of reproduction and …, 2000 - europepmc.org
Enhanced prostaglandin production and release by the placenta is an essential element in
the normal transition to labour in many animal species. In sheep, expression of …

Gestational-and labour-associated changes in the relative abundance of prostaglandin G/H synthase-1 and-2 mRNA in ovine placenta

GE Rice, KA Freed, MA Aitken… - Journal of Molecular …, 1995 - jme.bioscientifica.com
The aim of this study was to establish the gestational-and labour-associated variation in the
relative abundance of prostaglandin synthase-1 (PGHS-1) and prostaglandin synthase-2 …

[PDF][PDF] Localization of prostaglandin synthase type-1 (PGHS-1) mRNA and prostaglandin synthase type-2 (PGHS-2) mRNA in ovine myometrium and endometrium …

W Gibb, M Sun, S Gyomorey, SJ Lye… - Journal of endocrinology, 2000 - Citeseer
Increased prostaglandin production by tissues in the sheep uterus and placenta are thought
to be important for the onset of parturition. In the sheep placenta, this is most likely due to …

Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation

W Gibb, SG Matthews, JRG Challis - Biology of reproduction, 1996 - academic.oup.com
In numerous animal species, increased prostaglandin output by intrauterine tissues occurs
in association with parturition. In the sheep, prostaglandin H synthase (PGHS) is particularly …

Ontogeny and Regulation of Ovine Placental Prostaglandin E2 Synthase

RL Martin, WL Whittle, AC Holloway… - Biology of …, 2002 - academic.oup.com
Recent evidence suggests that ovine placental output of prostaglandin (PG) E2 rises
through late gestation partly because of a direct effect of cortisol on PGH2 synthase 2 (PGHS …

The expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase in ovine maternal uterine and fetal tissues during late gestation and labor

QI Zhang, WX Wu, JT Brenna, PW Nathanielsz - Endocrinology, 1996 - academic.oup.com
Gene expression of cytosolic phospholipase A2 (cPLA2) and prostaglandin endoperoxide
synthase (PGHS) 1 and 2 was studied in ovine maternal uterine and fetal tissues during …

[PDF][PDF] Increase in 15-hydroxyprostaglandin dehydrogenase activity in the ovine placentome at parturition and effect of oestrogen

SC Riley, R Leask, JV Selkirk, RW Kelly… - … of reproduction and …, 2000 - researchgate.net
Prostaglandin F2α (PGF2α) and PGE2 produced by the uterine tissues have long been
considered to be important during pregnancy for the regulation of blood flow (Carter, 1998) …

The pattern of glucocorticoid and estrogen receptors may explain differences in steroid dependency of intrauterine prostaglandin production at parturition in sheep

WL Whittle, AC Holloway, S Lye… - Journal of the …, 2006 - journals.sagepub.com
Background: We have recently described two distinct pathways of intrauterine prostaglandin
(PG) synthesis: a cortisol-dependent/estradiol-independent mechanism within trophoblast …