Pretreatment of MQA, a caffeoylquinic acid derivative compound, protects against H2O2-induced oxidative stress in SH-SY5Y cells

X Tian, L Gao, L An, X Jiang, J Bai, J Huang… - Neurological …, 2016 - Taylor & Francis
Objectives: Compound MQA (1, 5-O-dicaffeoyl-3-O-[4-malic acid methyl ester]-quinic acid) is
a natural caffeoylquinic acid derivative isolated from Arctium lappa L. roots. This study aims …

TCQA, a natural caffeoylquinic acid derivative attenuates H2O2-induced neuronal apoptosis by suppressing phosphorylation of MAPKs signaling pathway

Y Yang, Y Ding, H Gao, X Jiang, Q Zhao - Planta medica, 2022 - thieme-connect.com
1, 3, 5-Tri-O-caffeoyl quinic acid is a caffeoylquinic acid derivative isolated from the roots of
Arctium lappa L. Our previous studies have revealed that the ethyl acetate extract of the …

Caffeoylquinic acid derivatives protect SH-SY5Y neuroblastoma cells from hydrogen peroxide-induced injury through modulating oxidative status

XW Jiang, JP Bai, Q Zhang, XL Hu, X Tian… - Cellular and molecular …, 2017 - Springer
Oxidative stress has been confirmed as a contribution to the pathogenesis and
pathophysiology of many neurological disorders such as Alzheimer's disease and …

Treatment with MQA, a derivative of caffeoylquinic acid, provides neuroprotective effects against cerebral ischemia through suppression of the p38 pathway and …

L Chen, D Liu, Y Wang, X Liu, S Han, K Zhang… - Journal of Molecular …, 2019 - Springer
O-dicaffeoyl-3-O-(4-malic acid methylester)–quinic acid (MQA), extracted from Arctium lappa
L., has been observed to exert neuroprotective effects in vitro. The aim of this study was to …

Neuroprotective effects of Kukoamine B against hydrogen peroxide-induced apoptosis and potential mechanisms in SH-SY5Y cells

XL Hu, YX Niu, Q Zhang, X Tian, LY Gao… - Environmental …, 2015 - Elsevier
Oxidative stress mediates the cell damage in several neurodegenerative diseases, including
multiple sclerosis, Alzheimer's disease (AD) and Parkinson's disease (PD). This study aimed …

Protective Effects of Phillyrin on H2O2-induced Oxidative Stress and Apoptosis in PC12 Cells

T Wei, W Tian, H Yan, G Shao, G Xie - Cellular and molecular …, 2014 - Springer
Oxidative stress is a major component of harmful cascades activated in neurodegenerative
disorders. We sought to elucidate possible effects of phillyrin, an active constituent isolated …

Caffeic acid prevents hydrogen peroxide-induced oxidative damage in SH-SY5Y cell line through mitigation of oxidative stress and apoptosis.

A Ayna - Bratislava Medical Journal/Bratislavske Lekarske …, 2021 - search.ebscohost.com
AIM: The aim of this study was to examine the potential ameliorative effects of caffeic acid
(CA) on hydrogen peroxide (H< sub> 2 O< sub> 2)-induced neurodegeneration in a human …

Protective Effects of (E)-2-(1-Hydroxyl-4-Oxocyclohexyl) Ethyl Caffeine Against Hydrogen Peroxide-Induced Injury in PC12 Cells

B Chen, R Yue, Y Yang, H Zeng, W Chang… - Neurochemical …, 2015 - Springer
Abstract (E)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeine (HOEC), a naturally caffeic ester
isolated from Incarvillea mairei, has been reported to possess anti-inflammatory activity by …

Flavonoid Baicalein Modulates H2O2-Induced Mitogen-Activated Protein Kinases Activation and Cell Death in SK-N-MC Cells

M Moslehi, A Meshkini, R Yazdanparast - Cellular and molecular …, 2012 - Springer
It is believed that ROS-induced oxidative stress triggers numerous signaling pathways which
are involved in neurodegenerative diseases, including Alzheimer's disease. To find the …

Ethanol Extract of Maclura tricuspidata Fruit Protects SH-SY5Y Neuroblastoma Cells against H2O2-Induced Oxidative Damage via Inhibiting MAPK and NF-κB …

W Tian, S Heo, DW Kim, IS Kim, D Ahn, HJ Tae… - International Journal of …, 2021 - mdpi.com
Free radical generation and oxidative stress push forward an immense influence on the
pathogenesis of neurodegenerative diseases such as Alzheimer's disease and Parkinson's …