Background There is uncertainty about the impact of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI) …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients with
inborn errors of immunity (IEI) showed a similar infection-fatality rate, a lower incidence in …

Introduction Patients with inborn errors of immunity (IEI) have a compromised or
inappropriate immune response. Although they might be considered a high-risk group for …

Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …

Purpose There is still scarce data on SARS-CoV-2 infection in patients with Inborn Errors of
Immunity (IEI) and many unresolved questions. We aimed to describe the clinical outcome of …

We review the characteristics of SARS-CoV-2 infection in a large number of patients with IEI.
Overall, we found that combined immunodeficiencies, immune dysregulation disorders, and …

Despite the progress in the understanding how COVID-19 infection may impact
immunocompromised patients, the data on inborn errors of immunity (IEI) remain limited and …

Background Genetic deficiencies of immune system, referred to as inborn errors of immunity
(IEI), serve as a valuable model to study human immune responses. In a multicenter …

Since the arrival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
December 2019, its characterization as a novel human pathogen, and the resulting …

Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune
host defense and immunoregulation. Considering the predisposition to develop severe and …