Atezolizumab in locally advanced or metastatic urothelial cancer: a pooled analysis from the Spanish patients of the IMvigor 210 cohort 2 and 211 studies

M Sotelo, T Alonso-Gordoa, P Gajate… - Clinical and …, 2021 - Springer
Abstract Background The studies IMvigor 210 cohort 2 and IMvigor211 evaluated the
efficacy of atezolizumab in patients with locally advanced or metastatic urothelial cancer …

[HTML][HTML] Primary results from SAUL, a multinational single-arm safety study of atezolizumab therapy for locally advanced or metastatic urothelial or nonurothelial …

CN Sternberg, Y Loriot, N James, E Choy… - European urology, 2019 - Elsevier
Background Atezolizumab, a humanised monoclonal antibody targeting PD-L1, is approved
for locally advanced/metastatic urothelial carcinoma. SAUL evaluated atezolizumab in a …

Swiss experience of atezolizumab for platinum-pretreated urinary tract carcinoma: the SAUL study in real-world practice.

R Cathomas, J Schardt, M Pless, A Llado… - Swiss medical …, 2020 - boris.unibe.ch
AIMS OF THE STUDY Atezolizumab is an approved therapy for urothelial carcinoma based
on results from the IMvigor 210 and IMvigor211 phase II and III trials. The global SAUL study …

Clinical and economic outcomes in patients with metastatic urothelial carcinoma receiving first-line systemic treatment (the IMPACT UC I study)

MA Bilen, SB Robinson, A Schroeder, J Peng… - The …, 2023 - academic.oup.com
Abstract Background The IMPACT UC I study assessed real-world treatment patterns,
outcomes, healthcare resource utilization (HCRU), and costs in patients with metastatic …

FDA approval summary: atezolizumab or pembrolizumab for the treatment of patients with advanced urothelial carcinoma ineligible for cisplatin‐containing …

DL Suzman, S Agrawal, Y Ning, VE Maher… - The …, 2019 - academic.oup.com
Abstract The US Food and Drug Administration (FDA) granted accelerated approval to
atezolizumab and pembrolizumab in April and May 2017, respectively, for the treatment of …

[PDF][PDF] Atezolizumab for locally advanced/metastatic urothelia l carcinoma within the compassionate use program in Spain: the IMcompass study

MA Duran, JL Perez-Gracia, JA Arrija - J Clin Oncol, 2022 - cuba.dialogoroche.com
ATEZOLIZUMAB FOR LOCALLY ADVANCED/METASTATIC UROTHELIAL CARCINOMA WITHIN
THE COMPASSIONATE USE PROGRAM IN SPAIN: THE IMCOMPASS S Page 1 …

IMvigor130: A randomized, phase III study evaluating first-line (1L) atezolizumab (atezo) as monotherapy and in combination with platinum-based chemotherapy …

MD Galsky, E Grande, ID Davis, M De Santis… - 2018 - ascopubs.org
TPS4589 Background: Platinum-based chemo is the standard of care for most pts with
untreated mUC, although clinical outcomes remain poor. Atezo (anti–PD-L1) was approved …

Atezolizumab Plus Magrolimab, Niraparib, or Tocilizumab in Platinum-Refractory Metastatic Urothelial Carcinoma: A Phase Ib/II Open-Label, Randomized Umbrella …

A Drakaki, T Powles, A Bamias… - … Cancer Research: an …, 2023 - europepmc.org
Purpose The MORPHEUS platform was designed to identify early efficacy signals and
evaluate the safety of novel immunotherapy combinations across cancer types. The phase …

A pilot safety study of gemcitabine and cisplatin (GC) with atezolizumab (A) as first-line therapy in patients (pts) with metastatic urothelial cancer (mUC).

SA Funt, K Jatwani, M Makris, AM Regazzi, CH Lee… - 2019 - ascopubs.org
4559 Background: GC has a high overall response rate (ORR) but a high relapse rate in pts
with untreated mUC. Inhibition of programmed death-ligand 1 (PD-L1) with A can lead to …

Biological features and clinical outcomes in atezolizumab (atezo)-treated patients (pts) with metastatic urothelial cancer (mUC) of the upper vs lower urinary tract …

MD Galsky, R Banchereau, EE Kadel… - Annals of …, 2018 - annalsofoncology.org
Background: mUC arising from UTUC vs LTUC may involve distinct biology resulting in
different treatment responses & outcomes. However, this hypothesis has not been …