PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

Bioapplications of poly (amidoamine)(PAMAM) dendrimers in nanomedicine

N Taghavi Pourianazar, P Mutlu, U Gunduz - Journal of Nanoparticle …, 2014 - Springer
Abstract Poly (amidoamine)(PAMAM) dendrimers are a novel class of spherical, well-
designed branching polymers with interior cavities and abundant terminal groups on the …

Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy

J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …

Recent advances in preclinical research using PAMAM dendrimers for cancer gene therapy

P Tarach, A Janaszewska - International Journal of Molecular Sciences, 2021 - mdpi.com
Carriers of genetic material are divided into vectors of viral and non-viral origin. Viral carriers
are already successfully used in experimental gene therapies, but despite advantages such …

Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery

V Singh, A Sahebkar, P Kesharwani - European Polymer Journal, 2021 - Elsevier
Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …

Recent advances in dendrimer-based nanovectors for tumor-targeted drug and gene delivery

P Kesharwani, AK Iyer - Drug discovery today, 2015 - Elsevier
Highlights•Dendrimers are nanovectors with well-defined architecture and tunable surface
characteristics.•Dendrimers can take advantage of passive and active tumor targeting for …

Dendrimers in targeted drug delivery applications: A review of diseases and cancer

AK Mandal - International Journal of Polymeric Materials and …, 2021 - Taylor & Francis
Dendrimers in nanobiomedicine have attracted attention to overcome the biological barriers
because of their suitable characteristics such as nanosize, hyperbranching polymeric …

Surface functionalized dendrimers as controlled-release delivery nanosystems for tumor targeting

M Ghaffari, G Dehghan, F Abedi-Gaballu… - European Journal of …, 2018 - Elsevier
Dendrimers are nano-sized and three-dimensional macromolecules with well-defined
globular architecture and are widely used in various aspects such as drug and gene delivery …

PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy

B Surekha, NS Kommana, SK Dubey… - Colloids and Surfaces B …, 2021 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …