A large number of pharmacological studies have used capsaicin as a tool to activate many
physiological systems, with an emphasis on pain research but also including functions such …

Nociceptors, the subset of primary afferent neurons that detect pain-producing stimuli,
respond to a wide spectrum of physical and chemical stimuli that are potentially tissue …

Capsaicin ion channels are highly expressed in peripheral nervous terminals and involved
in pain and thermal sensations. One characteristic of the cloned VR1 receptor is its …

Capsaicin, a pharmacologically active agent found in chili peppers, causes burning and
itching sensation due to binding at the transient receptor potential vanilloid-1 (TRPV-1) …

The irritant action of capsaicin is mediated by the vanilloid receptor, VR1, which is
expressed in sensory neurons termed nociceptors. Capsaicin also desensitizes nociceptors …

Here, we investigated the mechanism of the antihyperalgesic effect of capsaicin cream in the
nerve injury-induced neuropathic pain model in mice. In naive mice, application of capsaicin …

The capsaicin receptor, VR1 (also known as TRPV1), is a ligand-gated ion channel
expressed on nociceptive sensory neurons that responds to noxious thermal and chemical …

Capsaicin, the pungent principle in chilli peppers has become a promising molecule for the
development of a new generation of analgesic-anti-inflammatory agents with a target …

The development of chronic pain is typically predicated by neuroplastic changes within the
spinal cord in response to persistent noxious stimuli, termed central sensitization …