TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1
S Kim, C Kang, CY Shin, SW Hwang… - Journal of …, 2006 - Soc Neuroscience
TRPV1, a cloned capsaicin receptor, is a molecular sensor for detecting adverse stimuli and
a key element for inflammatory nociception and represents biophysical properties of native …
a key element for inflammatory nociception and represents biophysical properties of native …
[HTML][HTML] Two vanilloid ligand bindings per channel are required to transduce capsaicin-activating stimuli
TY Liu, Y Chu, HR Mei, D Chang… - Frontiers in Molecular …, 2020 - frontiersin.org
The tetrameric capsaicin receptor transient receptor potential vanilloid 1 (TRPV1) in
mammals has evolved the capability to integrate pain signal arising from harmful …
mammals has evolved the capability to integrate pain signal arising from harmful …
Structure and function of TRPV1
M Tominaga, T Tominaga - Pflügers Archiv, 2005 - Springer
Capsaicin, the main ingredient in hot chili peppers, elicits a sensation of burning pain by
selectively activating sensory neurons that convey information about noxious stimuli to the …
selectively activating sensory neurons that convey information about noxious stimuli to the …
Capsaicin receptor immunoreactivity in the human trigeminal ganglion
M Hou, R Uddman, J Tajti, M Kanje, L Edvinsson - Neuroscience letters, 2002 - Elsevier
The cloned capsaicin receptor, also known as vanilloid receptor subtype 1 (VR1) receptor,
has been demonstrated to be an integral membrane protein with homology to a family of …
has been demonstrated to be an integral membrane protein with homology to a family of …
Complex regulation of capsaicin on intracellular second messengers by calcium dependent and independent mechanisms in primary sensory neurons
Intracellular second messengers play an important role in capsaicin-and analogous-induced
sensitization and desensitization in pain. Fluorescence Ca2+ imaging, enzyme …
sensitization and desensitization in pain. Fluorescence Ca2+ imaging, enzyme …
Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors
NB Ruparel, AM Patwardhan, AN Akopian… - Pain, 2008 - journals.lww.com
The transient receptor potential channel subtypes V1 (TRPV1) and A1 (TRPA1) play a
critical role in the development of hyperalgesia in inflammatory pain models. Although …
critical role in the development of hyperalgesia in inflammatory pain models. Although …
Use of capsaicin to treat pain: mechanistic and therapeutic considerations.
CMK Chung ManKyo, JN Campbell - 2016 - cabidigitallibrary.org
Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment
of neuropathic pain. The analgesia lasts for several months after a single treatment …
of neuropathic pain. The analgesia lasts for several months after a single treatment …
A “cute” desensitization of TRPV1
F Touska, L Marsakova, J Teisinger… - Current …, 2011 - ingentaconnect.com
Capsaicin and other vanilloids selectively excite and subsequently desensitize pain-
conducting nerve fibers (nociceptors) and this process contributes to the analgesic (and thus …
conducting nerve fibers (nociceptors) and this process contributes to the analgesic (and thus …
[PDF][PDF] Vascular effects of capsaicin receptor (TRPV1)
Á Czikora - dea.lib.unideb.hu
The TRPV1 is a nonselective cation channel (PCa/PNa≤ 10). TRPV1 belongs to the TRPV
subfamily of the large TRP (transient receptor potential) ion channel super family, whose …
subfamily of the large TRP (transient receptor potential) ion channel super family, whose …