Optimisation and method validation was assessed here for metabolic profiling analysis of
urine samples using UPLC–TOFMS. A longer run time of 31min revealed greater …

Biomarker selection through the metabolomics approach involves the acquisition of
nontargeted metabolic profiles. In this study, some critical factors that may affect this process …

Among the various biological matrices used in metabolomics, urine is a biofluid of major
interest because of its non-invasive collection and its availability in large quantities …

The applications of metabolomics as a methodology for providing better treatment and
understanding human disease continue to expand rapidly. In this review, covering the last …

Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …

Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …

The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …

Metabolomics analyses of urine have the potential to provide new information on the
detection and progression of many disease processes. However, urine samples can vary …

Urine is a popular biofluid for metabolomics studies due to its simple, non-invasive collection
and its availability in large quantities, permitting frequent sampling, replicate analyses, and …

Developing a workflow for metabolite profiling from biological fluids using mass
spectrometry is imperative to extract accurate information. In this study, urine samples from …