Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates.
While their antibacterial activity toward bacterial cells was the original focus for research …

Primitive innate defense mechanisms in the form of gene-encoded antimicrobial peptides
are now considered as potential candidates for the development of new therapeutics. They …

Host defence peptides (HDPs) are short, cationic amphipathic peptides that play a key role
in the response to infection and inflammation in all complex life forms. It is increasingly …

The rapidly increasing incidence of multidrug-resistant infections and the alarmingly low rate
of discovery of conventional antibiotics create an urgent need for alternative strategies to …

Host defense peptides can modulate the innate immune response and boost infection-
resolving immunity, while dampening potentially harmful pro-inflammatory (septic) …

Host defence peptides (HDPs), also known as antimicrobial peptides, are naturally occurring
polypeptides (~ 12-50 residues) composed of cationic and hydrophobic amino acids that …

Host defence peptides are found in all classes of life and are a fundamental component of
the innate immune response. Initially it was believed that their sole role in innate immunity …

Cationic host defense (antimicrobial) peptides were originally studied for their direct
antimicrobial activities. They have since been found to exhibit multifaceted …

The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …

Members of the cationic host defense (antimicrobial) peptide family are widely distributed in
nature, existing in organisms from insects to plants to mammals and non-mammalian …