Risk factors associated with a low glomerular filtration rate in primary aldosteronism

M Reincke, LC Rump, M Quinkler… - The Journal of …, 2009 - academic.oup.com
Context: Primary aldosteronism (PA) is associated with vascular end organ damage.
Objective: We evaluated the newly established German Conn's Registry for evidence of …

Effects of treating primary aldosteronism on renal function

BJ Kramers, C Kramers, JWM Lenders… - The Journal of …, 2017 - Wiley Online Library
Longstanding primary aldosteronism (PA) has deleterious effects on renal function, often
masked until treatment (adrenalectomy or spironolactone) is initiated. It has been suggested …

Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism

V Fourkiotis, O Vonend, S Diederich… - European journal of …, 2013 - academic.oup.com
Objective Primary aldosteronism (PA) has deleterious effects on kidney function
independent of blood pressure levels. Up to now, data on effectiveness of different PA …

Predictors of decreasing glomerular filtration rate and prevalence of chronic kidney disease after treatment of primary aldosteronism: renal outcome of 213 cases

Y Iwakura, R Morimoto, M Kudo, Y Ono… - The Journal of …, 2014 - academic.oup.com
Context: In primary aldosteronism (PA), glomerular hyperfiltration due to excessive
aldosterone is considered to underestimate actual renal damage. Objective: Our objectives …

Higher risk of chronic kidney disease and progressive kidney function impairment in primary aldosteronism than in essential hypertension. Case-control study

M Fernández-Argüeso, E Pascual-Corrales… - Endocrine, 2021 - Springer
Purpose To study the differences in the prevalence, risk, and grade of control of different
cardiometabolic comorbidities in patients with primary aldosteronism (PA) and essential …

Observational study mortality in treated primary aldosteronism: the German Conn's registry

M Reincke, E Fischer, S Gerum, K Merkle, S Schulz… - …, 2012 - Am Heart Assoc
In comparison with essential hypertension, primary aldosteronism (PA) is associated with an
increased risk of cardiovascular morbidity. To date, no data on mortality have been …

Renal damage in primary aldosteronism: a systematic review and meta-analysis

S Monticone, E Sconfienza, F D'Ascenzo… - Journal of …, 2020 - journals.lww.com
Objectives: In experimental animal models, exogenous aldosterone excess has been linked
to the progression of renal disease. However, the evidence of an increased risk of renal …

Renal impairment is closely associated with plasma aldosterone concentration in patients with primary aldosteronism

A Kawashima, M Sone, N Inagaki… - European Journal of …, 2019 - academic.oup.com
Objective Several clinical studies have reported that renal impairments are sometimes
observed in patients with primary aldosteronism (PA). We analyzed the prevalence of renal …

Kidney impairment in primary aldosteronism

VC Wu, SY Yang, JW Lin, BW Cheng, CC Kuo… - Clinica Chimica …, 2011 - Elsevier
Background Kidney impairment is noted in primary aldosteronism (PA), and probably
initiated by glomerular hyperfiltration. Methods A prospectively defined survey was …

Cardiovascular complications associated with primary aldosteronism: a controlled cross-sectional study

S Savard, L Amar, PF Plouin, O Steichen - Hypertension, 2013 - Am Heart Assoc
A higher risk of cardiovascular events has been reported in patients with primary
aldosteronism (PA) than in otherwise similar patients with essential hypertension (EH) …