Cholangiocarcinoma, which is the most common invasive malignant tumor of the biliary tract,
has poor prognosis. There is evidence suggesting that hypoxia-inducible factor 1α (HIF1α) …

Purpose Hepatocyte nuclear factor 6 (HNF6) is a liver-enriched transcription factor and
highly expressed in mature bile duct epithelial cells. This study sought to investigate the role …

Abstract Background and Aims Hypoxia represents one of the most pervasive
microenvironmental stresses in HCC due to the overwhelming growth and inadequate blood …

To date, a large set of long non-coding RNAs (lncRNAs) have been identified in
tumorigenesis and progression. The present study focused on functions and mechanisms of …

Abstract Interferon regulatory factor 1 (IRF1) has been found to serve as a tumor suppressor
in cholangiocarcinoma, and enabled prediction of clinical progression and prognosis in our …

LncRNAs were a group of RNAs, which can be a regulator or master in biological activities
of cancer cells. HIF1A-AS2 belongs to this group, and it has been verified to be able to affect …

HIF-1α is an important transcriptional factor, which plays roles in cancer development and
progression. But its regulation by miRNAs is not clear. Here, to investigate the regulation of …

Cholangiocarcinoma (CCA) is a deadly disease that poorly responds to chemotherapy and
radiotherapy and whose incidence has increased worldwide. Furthermore, long noncoding …

Long non-coding RNA LINC00152 had been reported as an oncogene in gastric and
hepatocellular cancer. In this study, we show that LINC00152 is overexpressed in …

Background Long non-coding RNAs (lncRNAs) are essential for tumorigenesis and
progression of diverse cancers. This study aims to investigate the roles of lncRNAs on renal …