Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4‐R7 System

F Barbieri, S Thellung, R Würth, F Gatto… - International journal …, 2014 - Wiley Online Library
Chemokines are chemotactic regulators of immune surveillance in physiological and
pathological conditions such as inflammation, infection, and cancer. Several chemokines …

The chemokine SDF1/CXCL12: a novel autocrine/paracrine factor involved in pituitary adenoma development

F Barbieri, A Bajetto, A Pattarozzi, M Gatti… - The Open …, 2011 - benthamopen.com
The relevance of the chemokine/chemokine receptor system has broaden to several tissues.
Besides their physiologic role as chemotactic cytokines in immune surveillance, it is now …

[PDF][PDF] Role of stromal cell-derived factor 1 (SDF1/CXCL12) in regulating anterior pituitary function

F Barbieri, A Bajetto, C Porcile… - Journal of …, 2007 - jme.bioscientifica.com
Chemokines are key factors involved in the regulation of immune response, through the
activation and control of leukocyte traffic, lymphopoiesis and immune surveillance. However …

Signalling Pathway Mediated by CXCR7, an Alternative Chemokine Receptor for Stromal‐Cell Derived Factor‐1α, in AtT20 Mouse Adrenocorticotrophic Hormone …

D Yoshida, R Nomura… - Journal of …, 2009 - Wiley Online Library
Stromal cell‐derived factor (SDF)‐1 and its receptor, CXCR4, have been identified in both
neurones and glia of many brain areas. Previous studies have mainly focused on the role of …

CXCL13 and its receptor CXCR5 in cancer: inflammation, immune response, and beyond

MG Kazanietz, M Durando, M Cooke - Frontiers in endocrinology, 2019 - frontiersin.org
It is well-established that the chemokine CXC motif ligand 13 (CXCL13) and its receptor, the
G-protein coupled receptor (GPCR) CXCR5, play fundamental roles in inflammatory …

[HTML][HTML] Role of chemokines in thyroid cancer microenvironment: is CXCL8 the main player?

M Rotondi, F Coperchini, F Latrofa… - Frontiers in …, 2018 - frontiersin.org
Tumor-related inflammation does influence the biological behavior of neoplastic cells and
ultimately the patient's outcome. With specific regard to thyroid cancer, the issue of tumor …

CXCR4: From Signaling to Clinical Applications in Neuroendocrine Neoplasms

D Sanchis-Pascual, MI Del Olmo-García… - Cancers, 2024 - mdpi.com
Simple Summary Neuroendocrine neoplasms are a heterogeneous group of malignant
tumors that originate from the diffuse endocrine system. They generally have a slow course …

In the ovine pituitary, CXCR4 is localized in gonadotropes and somatotropes and increases with elevated serum progesterone

NS Sanchez, KE Quinn, AK Ashley… - Domestic animal …, 2018 - Elsevier
The pituitary is the central endocrine regulator of reproduction and in addition to various
hormones regulating its actions, other molecules, such as chemokines, influence pituitary …

Expression of chemokine CXCL12 and its receptor CXCR4 in folliculostellate (FS) cells of the rat anterior pituitary gland: the CXCL12/CXCR4 axis induces …

K Horiguchi, C Ilmiawati, K Fujiwara, T Tsukada… - …, 2012 - academic.oup.com
The anterior pituitary gland is composed of five types of hormone-producing cells plus
folliculostellate (FS) cells, which do not produce classical anterior pituitary hormones. FS …

Chemokines as modulators of neuroendocrine functions

W Rostene, JC Buckingham - Journal of molecular …, 2007 - jme.bioscientifica.com
Chemokines are small secreted proteins with chemoattractant properties for immune cells.
Besides their role in the immune system, chemokines and their receptors may play important …