[HTML][HTML] Alpinumisoflavone exhibits the therapeutic effect on prostate cancer cells by repressing AR and co-targeting FASN-and HMGCR-mediated lipid and …

P Basavaraj, P Ruangsai, PF Hsieh, WP Jiang, DT Bau… - Life, 2022 - mdpi.com
Prostate cancer (PCa) is the most common cancer in men, and this has been mainly noticed
in Western and Asian countries. The aggregations of PCa and castration-resistant PCa …

Cell suspension culture extract of Eriobotrya japonica attenuates growth and induces apoptosis in prostate cancer cells via targeting SREBP-1/FASN-driven …

PF Hsieh, WP Jiang, P Basavaraj, SY Huang… - Phytomedicine, 2021 - Elsevier
Background Castration-resistant prostate cancer (CRPC) is one of the main causes of male
cancer mortality. There is currently no effective treatment to cure this deadly prostate cancer …

[HTML][HTML] Afzelin exhibits anti-cancer activity against androgen-sensitive LNCaP and androgen-independent PC-3 prostate cancer cells through the inhibition of LIM …

KC Zhu, JM Sun, JG Shen, JZ Jin, F Liu… - Oncology …, 2015 - spandidos-publications.com
Prostate cancer presents high occurrence worldwide. Medicinal plants are a major source of
novel and potentially therapeutic molecules; therefore, the aim of the present study was to …

Osajin displays potential antiprostate cancer efficacy via impairment of fatty acid synthase and androgen receptor expression

SY Huang, GJ Huang, PF Hsieh, HC Wu… - The …, 2019 - Wiley Online Library
Abstract Background Currently, antiprostate cancer (PCa) drugs, including androgen
deprivation therapy (ADT), are initially effective; however, most patients with PCa who …

Capilliposide B inhibits the migration of prostate cancer by inducing autophagy through the ROS/AMPK/mTOR pathway

L Wang, H Han, Y Feng, J Ma, Z Han, R Li… - Phytotherapy …, 2023 - Wiley Online Library
Abstract Capilliposide B (CPS‐B), a novel oleanane triterpenoid saponin derived from
Lysimachia capillipes Hemsl, is a potent anticancer agent. However, its anticancer …

Ericifolin: a novel antitumor compound from allspice that silences androgen receptor in prostate cancer

N Shamaladevi, DA Lyn, KA Shaaban, L Zhang… - …, 2013 - academic.oup.com
Silencing of androgen receptor (AR) signaling is a specific and effective mechanism to cure
cancer of the prostate (CaP). In this study, the isolation and characterization of a compound …

[HTML][HTML] AKT, a Key Transmitter of HIF-1α and AR Signaling Pathways, Has a Critical Role in the Apigetrin-Mediated Anti-Cancer Effects in Prostate Cancer Cells

YK Lee, JE Kim, Y Xu, H Han, JH Lee, HJ Lee - Biomedicines, 2022 - mdpi.com
Apigetrin is a flavonoid glycoside phytochemical that is derived from various herbs and
exhibits several beneficial biological activities, including anti-oxidant, anti-inflammatory, anti …

Alpinumisoflavone suppresses hepatocellular carcinoma cell growth and metastasis via NLRP3 inflammasome-mediated pyroptosis

Y Zhang, H Yang, M Sun, T He, Y Liu, X Yang… - Pharmacological …, 2020 - Springer
Aim This research aims to explore the effect of alpinumisoflavone (AIF) as an anti-cancer
drug for the treatment of patients with hepatocellular carcinoma (HCC). Methods Cell …

Capilliposide C derived from Lysimachia capillipes Hemsl inhibits growth of human prostate cancer PC3 cells by targeting caspase and MAPK pathways

R Li, L Zhang, L Zhang, D Chen, J Tian, L Cao… - … urology and nephrology, 2014 - Springer
Prostate cancer, a common malignant tumor of the genitourinary system among elderly
males, is difficult to cure. Capilliposide C (CPS-C) is a novel oleanane triterpenoid saponin …

[HTML][HTML] Alpinumisoflavone disrupts endoplasmic reticulum and mitochondria leading to apoptosis in human ovarian cancer

T Hong, J Ham, G Song, W Lim - Pharmaceutics, 2022 - mdpi.com
Alpinumisoflavone is a prenylated isoflavonoid derived from the Cudrania tricuspidate fruit
and Genista pichisermolliana. Alpinumisoflavone has anticancer properties in a variety of …