Mercaptopurine is a medication employed to treat autoimmune illnesses and cancer.
However, due to its poor solubility, quick metabolism, and possible side effects, it is not very …

Background Acute lymphoblastic leukemia (ALL) is the most common hematologic
malignancy in children. It requires a long and rigorous course of chemotherapy treatments. 6 …

Nanotechnology is the science of nanoscale, which is the scale of nanometers or one
billionth of a meter. Nanotechnology encompasses a broad range of technologies, materials …

6-Mercaptopurine (6-MP) is a well-known immunosuppressive medication with proven anti-
proliferative activities. 6-MP possesses incomplete and highly variable oral absorption due …

Background Combination therapy employing multiple drugs has been shown to enhance the
efficacy of cancer treatment. Chlorambucil (Chl) and 6-mercaptopurine (6MP) are the first …

Nanoformulations are a novel method of administration of the drug, approved by the USFDA.
These formulations are able to deliver the drug molecules to the target site more effectively …

Initially developed as a synthetic analogue of insulin, pentamidine (PTM) is an antimicrobial
drug that has recently shown in vitro and in vivo anticancer activity. Nevertheless, systemic …

The present work was an attempt to investigate the potentialities of multi-walled carbon
nanotubes (MWCNT) as a carrier for targeting 6 Mercaptopurine to cancer tissues. MWCNTs …

Cancer arises when the homeostatic balance between cell growth and death is disturbed. A
current standard treatment for cancer not only targets cancer cells but also affects normal …

The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of
the most common cancer treatment modalities is chemotherapy which involves …