Colorectal cancer (CRC) is one of the most common malignancies in the western world. Its
high mortality rates are particularly related to the occurrence of liver metastases. Many …

Colorectal cancer (CRC) is the third most frequent cancer and the third leading cause of
cancer deaths in the United States (American Cancer Society, Cancer facts and figures …

Liver metastasis is a leading cause of death in patients with colorectal cancer. Investigating
the mechanisms of liver metastasis and control of disease progression are important …

Simple Summary In its early stages, colorectal cancer (CRC) is a localized tumor, but when it
metastasizes, it has dramatic consequences. Murine models in CRC research are important …

Colorectal cancer is one of the most common malignancies in the world. Many mouse
models have been developed to evaluate features of colorectal cancer in humans. These …

Colorectal cancer (CRC) is a malignant disease that is the second most common cancer
worldwide. CRC arises from the complex interactions among a variety of genetic and …

Introduction: Despite increased screening rates and advances in targeted therapy, colorectal
cancer (CRC) remains the third leading cause of cancer-related mortality. CRC models that …

Liver metastases of colorectal carcinoma occur in about 50–60% of patients. To improve
survival of these patients, there is an urgent need for new treatment strategies. For this …

Colorectal cancer is a heterogeneous disease that afflicts a large number of people in the
USA. The use of animal models has the potential to increase our understanding of …

Background: Metastasis is one of the main reasons for colorectal cancer (CRC)-related
deaths due to the lack of effective therapeutics mainly for liver metastasis. In the present …