From the moment a cell is on the path to malignant transformation, its interaction with other
cells from the microenvironment becomes altered. The flow of molecular information is at the …

Cells are social entities. As such, they need to interact and communicate with each other, in
order to be able to build organized structures of tissues, organs, and organisms or to ensure …

Gap junction proteins are expressed in cancer stem cells and non-stem cancer cells of many
tumors. As the morphology and assembly of gap junction channels are crucial for their …

Cancer's complexity is in part due to the presence of intratumor heterogeneity and the
dynamic nature of cancer cell plasticity, which create substantial obstacles in effective …

The tumor microenvironment (TME) is a complex system composed of multiple cells, such as
non-cancerous fibroblasts, adipocytes, immune and vascular cells, as well as signal …

Although they tend to develop some independence upon malignant transformation, tumor
cells and tumors remain “social” moieties. In many steps during tumor progression, tumor …

The delineation of key molecular pathways has enhanced our knowledge of the biology of
tumor microenvironment, tumor dissemination, and carcinogenesis. The complexities of cell …

The role of intercellular communication is increasingly recognized as being critical to
tumoral invasion, metastasis, and development of resistance to therapy. The recent …

Intercellular communication is vital to the ecosystem of cancer cell organization and
invasion. Identification of key cellular cargo and their varied modes of transport are important …

The current special issue entitled “Role of tunneling nanotubes (TNTs) in carcinogenesis”
was designed to discuss the role of cell‐to‐cell communication, especially TNTs, in cancer …