This review focuses on the design, synthesis and pharmacological effects of non-steroidal
anti-inflammatory (NSAIDs) mefenamic acid which is an anthranilic acid derivative …

Background: Non steroidal anti-inflammatory drugs are the most widely prescribed drugs to
manage pain and inflammatory conditions, but their long term use is associated with …

Clinical use of mefenamic acid has generally declined in an era where other NSAID use has
flourished. While having modes of action and general toxicities similar to other NSAIDs …

The inflammatory process is, as known, a pathological symptom of many illnesses.
Therefore, the regulation of the inflammatory reaction, including that by means of …

Mefenamic acid (MFA) is a non-steroidal anti-inflammatory drug that belongs to the
anthranilic acid derivative family. It is used to relieve mild to moderate pain. The present …

A group of amino derivatives [4-aminobenzenesulfonamide, 4-amino-N¹
methylbenzenesulfonamide, or N¹-(4-aminophenylsulfonyl) acetamide] bound to carboxyl …

Mefenamic acid is analgesic and anti-pyretic used to treat menstrual pain. A simple assay
method by HPLC was developed and validated for mefenamic acid tablet (Ponstan) …

This work aims to design, synthesis and preliminary pharmacological evaluation of
mefenamic acid and indomethacin derivatives as potential anti-inflammatory agents with …

Abstract prodrugs are bioreversible derivatives of drug molecules that undergo
intermolecular or intramolecular reactions by enzymatic or chemical biotransformation in the …

Objective: The purpose of the study was to synthesize prodrugs of mefenamic acid, to be
used as Anti inflammatory drug with fewer adverse effects. Methods: The drug was …