Coordination between stochastic and deterministic specification in the Drosophila visual system

M Courgeon, C Desplan - Science, 2019 - science.org
INTRODUCTION Neuronal fate decisions must be coordinated across brain regions so that
the proper stoichiometry of distinct afferents and their target neurons is established. Many …

Two types of Drosophila R7 photoreceptor cells are arranged randomly: A model for stochastic cell‐fate determination

ML Bell, JB Earl, SG Britt - Journal of Comparative Neurology, 2007 - Wiley Online Library
The R7 photoreceptor cells of the Drosophila retina are ultraviolet sensitive and are thought
to mediate color discrimination and polarized light detection. In addition, there is growing …

[PDF][PDF] Regional modulation of a stochastically expressed factor determines photoreceptor subtypes in the Drosophila retina

SU Thanawala, J Rister, GW Goldberg, A Zuskov… - Developmental cell, 2013 - cell.com
Stochastic mechanisms are sometimes utilized to diversify cell fates, especially in nervous
systems. In the Drosophila retina, stochastic expression of the PAS-bHLH transcription factor …

Determination of Drosophila photoreceptors: timing is everything

CA Brennan, K Moses* - Cellular and Molecular Life Sciences CMLS, 2000 - Springer
This review covers recent findings concerning the specification of the photoreceptor
subtypes in the Drosophila eye. Particular attention is paid to aspects of retinal patterning …

Integration of temporal and spatial patterning generates neural diversity

T Erclik, X Li, M Courgeon, C Bertet, Z Chen… - Nature, 2017 - nature.com
In the Drosophila optic lobes, 800 retinotopically organized columns in the medulla act as
functional units for processing visual information. The medulla contains over 80 types of …

ON selectivity in the Drosophila visual system is a multisynaptic process involving both glutamatergic and GABAergic inhibition

S Molina-Obando, JF Vargas-Fique, M Henning, B Gür… - Elife, 2019 - elifesciences.org
Sensory systems sequentially extract increasingly complex features. ON and OFF pathways,
for example, encode increases or decreases of a stimulus from a common input. This …

The Drosophila visual system: From neural circuits to behavior

Y Zhu - Cell adhesion & migration, 2013 - Taylor & Francis
A compact genome and a tiny brain make Drosophila the prime model to understand the
neural substrate of behavior. The neurogenetic efforts to reveal neural circuits underlying …

Switch of rhodopsin expression in terminally differentiated Drosophila sensory neurons

SG Sprecher, C Desplan - Nature, 2008 - nature.com
Specificity of sensory neurons requires restricted expression of one sensory receptor gene
and the exclusion of all others within a given cell. In the Drosophila retina, functional identity …

Molecular logic behind the three-way stochastic choices that expand butterfly colour vision

M Perry, M Kinoshita, G Saldi, L Huo, K Arikawa… - Nature, 2016 - nature.com
Butterflies rely extensively on colour vision to adapt to the natural world. Most species
express a broad range of colour-sensitive Rhodopsin proteins in three types of ommatidia …

[PDF][PDF] Activity-independent prespecification of synaptic partners in the visual map of Drosophila

PR Hiesinger, RG Zhai, Y Zhou, TW Koh, SQ Mehta… - Current biology, 2006 - cell.com
Specifying synaptic partners and regulating synaptic numbers are at least partly activity-
dependent processes during visual map formation in all systems investigated to date [1–5] …