Sialic acid‐containing glycans play important roles in biology, but their synthesis by
standard chemical approaches is challenging. Enzymatic assembly is generally a better …

Sialic acids are a family of negatively charged monosaccharides which are commonly
presented as the terminal residues in glycans of the glycoconjugates on eukaryotic cell …

Conspectus Sialic acids are fascinating negatively charged nine-carbon monosaccharides.
Sialic acid-containing glycans and glycoconjugates are structurally diverse, functionally …

Although the vital roles of structures containing sialic acid in biomolecular recognition are
well documented, limited information is available on how sialic acid structural modifications …

Highlights•Chemical synthesis provided access to O-linked and S-linked oligosialic
acids.•Oxazolidinone-protected sialyl donors enable α-selective sialylation.•Enzymatic …

Sialic acids on the non-reducing terminus of sialylgylcans are abundantly expressed on the
surface of mammalian cells. They play vital roles in cell-cell interactions and during infection …

Sialic acids are important recognition sites in protein-and lipid-linked glycans of higher
organisms and of select bacteria and protozoa. They are also prominent in human milk …

Sialic acid is an important component of cell surface glycans, which are responsible for
many vital body functions and should therefore be thoroughly studied to understand their …

Sialic acids are characterized as ubiquitous sugar carboxylic acid with 9-carbon atoms as a
backbone, often involved in important cell surface communications and infection processes …

Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl
transfer reactions, since chemical sialylations usually give only low yields and lead to poor …