In order to survive within the macrophages of its host organism, the protozoan parasite
Leishmania inhibits a number of critical, gamma interferon (IFN-γ)-inducible, macrophage …

Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as
well as being responsible for widespread suffering in allergies. However, the precise …

Visceral Leishmaniasis (VL), caused by the intracellular protozoan Leishmania donovani, is
characterized by relentlessly increasing visceral parasite replication, cachexia, massive …

IL-9 fate reporter mice established type 2 innate lymphoid cells (ILC2s) as major producers
of this cytokine in vivo. Here we focus on the role of IL-9 and ILC2s during the lung stage of …

Leishmania donovani protozoan parasites, the causative agent of visceral leishmaniasis,
establish an infection partly by interfering with cytokine signaling in the host macrophages …

Infection of C57BL/6 mice with most Leishmania major strains results in a healing lesion and
clearance of parasites from the skin. Infection of C57BL/6 mice with the L. major Seidman …

Inflammatory monocytes can be manipulated by environmental cues to perform multiple
functions. To define the role of monocytes during primary or secondary infection with an intra …

We investigated the immune responses in mice lacking CCR2, CCR5, or macrophage
inflammatory protein-1α (MIP-1α), a ligand for CCR5, in two situations: following T cell …

Participation of B cells in the immune response by various antibody-independent
mechanisms has recently been uncovered. B cells producing cytokines have been …

Inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production was
demonstrated in J774-G8 macrophages infected with Leishmania (L.) amazonensis …