Interferon-γ: the Jekyll and Hyde of malaria
T King, T Lamb - PLoS pathogens, 2015 - journals.plos.org
Interferon gamma (IFN-γ) is a key mediator of inflammatory immune responses induced
primarily by interleukin-12 (IL-12). IFN-γ secretion by both innate and adaptive immune cells …
primarily by interleukin-12 (IL-12). IFN-γ secretion by both innate and adaptive immune cells …
Targeting macrophage histone H3 modification as a leishmania strategy to dampen the NF-κB/NLRP3-mediated inflammatory response
H Lecoeur, E Prina, T Rosazza, K Kokou, P N'Diaye… - Cell reports, 2020 - cell.com
Aberrant macrophage activation during intracellular infection generates immunopathologies
that can cause severe human morbidity. A better understanding of immune subversion …
that can cause severe human morbidity. A better understanding of immune subversion …
Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity
A Haque, SE Best, MM De Oca… - The Journal of …, 2014 - Am Soc Clin Investig
Many pathogens, including viruses, bacteria, and protozoan parasites, suppress cellular
immune responses through activation of type I IFN signaling. Recent evidence suggests that …
immune responses through activation of type I IFN signaling. Recent evidence suggests that …