Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury
S Hou, DM Carson, D Wu, MC Klaw, JD Houlé… - Experimental …, 2016 - Elsevier
Dopamine (DA) neurons in the mammalian central nervous system are thought to be
restricted to the brain. DA-mediated regulation of urinary activity is considered to occur …
restricted to the brain. DA-mediated regulation of urinary activity is considered to occur …
Spinal dopaminergic mechanisms regulating the micturition reflex in male rats with complete spinal cord injury
Y Qiao, ZD Brodnik, S Zhao, CT Trueblood… - Journal of …, 2021 - liebertpub.com
Traumatic spinal cord injury (SCI) often causes micturition dysfunction. We recently
discovered a low level of spinally-derived dopamine (DA) that regulates recovered bladder …
discovered a low level of spinally-derived dopamine (DA) that regulates recovered bladder …
Dopamine D‐1 receptor‐mediated inhibition of micturition reflex by central dopamine from the substantia nigra
N Yoshimura, O Yoshida, M Sasa… - Neurourology and …, 1992 - Wiley Online Library
We examined the role of dopamine derived from the pars compacta of the substantia nigra
(SN) in the micturition reflex using a‐chloralose anesthetized cats. Repetitive stimuli applied …
(SN) in the micturition reflex using a‐chloralose anesthetized cats. Repetitive stimuli applied …
Altered glutamate receptor function during recovery of bladder detrusor-external urethral sphincter coordination in a rat model of spinal cord injury
V Pikov, JR Wrathall - Journal of Pharmacology and Experimental …, 2002 - ASPET
Coordination of the bladder detrusor and the external urethral sphincter is a supraspinally
controlled reflex that is essential for efficient micturition. This coordination is permanently lost …
controlled reflex that is essential for efficient micturition. This coordination is permanently lost …
GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats
M Miyazato, K Sasatomi, S Hiragata… - The Journal of …, 2008 - auajournals.org
Purpose: We investigated the effects of intrathecal application of γ-aminobutyric acid A and
B receptor agonists on detrusor overactivity in spinal cord injured rats. Materials and …
B receptor agonists on detrusor overactivity in spinal cord injured rats. Materials and …
Roles of Glycinergic and Gamma‐aminobutyric‐ergic Mechanisms in the Micturition Reflex in Rats
M Miyazato, N Yoshimura, S Nishijima… - LUTS: Lower Urinary …, 2009 - Wiley Online Library
The micturition reflex is one of the autonomic reflexes mediated by the spinobulbospinal
reflex pathway that passes through the pontine micturition center. In the central nervous …
reflex pathway that passes through the pontine micturition center. In the central nervous …
Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury
N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …
Changes in afferent activity after spinal cord injury
WC de Groat, N Yoshimura - Neurourology and Urodynamics …, 2010 - Wiley Online Library
Aims To summarize the changes that occur in the properties of bladder afferent neurons
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …
Neurogenic bladder model for spinal cord injury: spinal cord microdialysis and chronic urodynamics
CP Smith, GT Somogyi, ET Bird, MB Chancellor… - Brain research …, 2002 - Elsevier
We describe an animal model to study neurotransmitter changes in parallel with urodynamic
testing following Spinal Cord Injury (SCI). Urodynamic access was achieved using a …
testing following Spinal Cord Injury (SCI). Urodynamic access was achieved using a …
Chronic spinal cord injury causes upregulation of serotonin (5‐HT)2A and 5‐HT2C receptors in lumbosacral cord motoneurons
N Cao, J Ni, X Wang, H Tu, B Gu, J Si, G Wu… - BJU …, 2018 - Wiley Online Library
Objectives To investigate whether the voiding dysfunction caused by spinal cord injury (SCI)
in rats can be improved by iv administration of the serotonin (5‐HT) 2A/2C receptor agonist …
in rats can be improved by iv administration of the serotonin (5‐HT) 2A/2C receptor agonist …
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