Introduction: Gliomas are considered the most malignant form of brain tumors, and ranked
among the most aggressive human cancers. Despite advance standard therapy the …

Malignant gliomas represent one of the most aggressive forms of brain cancer. Recent
advances in the understanding of the deregulated molecular pathways of gliomas have …

The impact of cytotoxic therapies on the outcome of glioblastoma has been modest thus far.
Yet it is clear that subsets of high-grade gliomas exist that are sensitive to treatment. Patients …

Introduction: The field of neuro-oncology has experienced significant advances in recent
years. More is known now about the molecular and genetic characteristics of glioma than …

Glioma is the most common primary intracranial malignancy in the central nervous system.
At present, the most important treatment option is surgical resection of the tumor combined …

Introduction: Outcome for patients with glioblastoma (GBM), the most common malignant
primary brain tumor among adults, remains poor. However, two key treatment options have …

(1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central
nervous system. Through many years, research has brought various advances in …

Simple Summary Despite the continuous development of treatment technology,
glioblastoma remains a challenge for modern medicine. The standard of care remains a …

Due to its localisation, rapid onset, high relapse rate and resistance to most currently
available treatment methods, glioblastoma multiforme (GBM) is considered to be the …

The identification of molecular markers associated with tumor but not with normal tissue has
allowed the development of highly specific, targeted therapies for the treatment of cancer …