Multiple sclerosis (MS) is a chronic inflammatory disease mediated by a complex interaction
between the autoreactive lymphocytes and the effector myeloid cells within the central …

Multiple sclerosis (MS) is characterized by pathological inflammation that results from the
recruitment of lymphoid and myeloid immune cells from the blood into the brain. Due to …

Previously, we have established two distinct progressive multiple sclerosis (MS) models by
induction of experimental autoimmune encephalomyelitis (EAE) with myelin oligodendrocyte …

Objective Myeloid cells, including macrophages and dendritic cells, are a prominent
component of central nervous system (CNS) infiltrates during multiple sclerosis (MS) and the …

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the myelination of the
neurons present in the central nervous system (CNS). The exact etiology of MS development …

Background Multiple sclerosis (MS), an autoimmune disease of the central nervous system
(CNS), can be suppressed in its early stages but eventually becomes clinically progressive …

The role of microglia and monocyte-derived macrophages in experimental autoimmune
encephalomyelitis pathogenesis has been controversial. To gain insight into their respective …

Abstract Background Multiple Sclerosis (MS) is a potentially devastating autoimmune
neurological disorder, which characteristically induces demyelination of white matter in the …

INTRODUCTION Under homeostasis, the central nervous system (CNS) hosts microglia
(MG) and CNS-associated macrophages (CAMs). During experimental autoimmune …

Myelin-reactive T cells have been identified in patients with multiple sclerosis (MS) and
healthy subjects with comparable frequencies, but the contribution of these autoreactive T …