Background Heterogeneity of clinical presentation of chronic obstructive pulmonary disease
(COPD) attributes to different pathological basis. High-resolution computed tomography …

Computed tomography has facilitated recognition that chronic obstructive pulmonary
disease is not a single disease but encompasses several overlapping entities, including …

Chronic obstructive pulmonary disease is a heterogeneous condition of the lungs and body.
Techniques in chest imaging and quantitative image analysis provide novel in vivo insight …

The diagnosis, prognostication, and differentiation of phenotypes of COPD can be facilitated
by CT scan imaging of the chest. CT scan imaging of the chest is a prerequisite for lung …

Chronic obstructive pulmonary disease (COPD) is heterogenous in its clinical manifestations
and disease progression. Patients often have disease courses that are difficult to predict with …

Parametric response mapping (PRM) of paired CT lung images has been shown to improve
the phenotyping of COPD by allowing for the visualization and quantification of non …

Purpose The diagnosis and severity of chronic obstructive pulmonary disease (COPD) are
defined by airflow limitation using spirometry. However, COPD has diverse clinical features …

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease.
Not all patients with COPD respond to available drugs. Identifying respondents to therapy is …

Study objectives The aim of this study was to investigate the relationship between high-
resolution CT (HRCT) lung attenuation measurements, acquired under spirometric control of …

The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …