Bosentan Hydrochloride (BOS) is poorly water soluble, high molecular weight and eleven
hydrogen bond acceptors. Thus, it exhibits poor bioavailability. A new Solid-Self Emulsifying …

Spironolactone is aldosterone antagonist drug belonging to the category of potassium
sparing diuretics administered orally that has absolute bioavailability of only 68% due to the …

Objective: The objective of this work was to improve the solubility and dissolution rate of
Nifedipine by preparing a solid-self micro emulsifying drug delivery system (Solid-smedds) …

Improvement of bio-availability of poorly water soluble drugs presents one of the furthermost
challenge in drug formulations. One of the most admired and commercially viable …

Sertraline is a selective serotonin reuptake inhibitors used as major therapeutic advances in
psychiatry and is drug of choice for treatment of major depressive disorders. The drug (free …

Objective: The formulation of self-emulsifying drug delivery system of drugs is to enhance
the solubility and bioavailability. More than 40% of available drugs exhibit poor water …

Objectives: To enhance solubility, dissolution, and permeability of poorly water-soluble drug
Ezetimibe (EZE) using a self-nano emulsifying drug delivery system (SNEDDS). Methods …

The aim of the study was to develop and optimize Self-nanoemulsifying drug delivery
systems (SNEDDS) for the improvement of solubility and dissolution of an anti-allergic drug …

Aim of present investigation was to develop Solid self micro emulsifying drug delivery
system (S-SMEDDS) of cardiovascular drugs such as Telmisartan (TEL) and Verapamil …

Hypertension is main risk factor for cardiovascular disease. Valsartan is a widely used,
effective and welltolerated antihypertensive agent by specifically blocking the action of …