[PDF][PDF] The role of reactive oxygen species and oxidative stress in mediating particulate matter injury

T Xia, M Kovochich, A Nel - Clin Occup Environ Med, 2006 - academia.edu
Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress

AE Nel, D Diaz-Sanchez, N Li - Current opinion in pulmonary …, 2001 - journals.lww.com
We review the literature indicating that the adverse health effects of ambient particulate
matter involve the generation of oxidative stress and inflammation, as well as …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Oxidative stress and air pollution exposure

M Lodovici, E Bigagli - Journal of toxicology, 2011 - Wiley Online Library
Air pollution is associated with increased cardiovascular and pulmonary morbidity and
mortality. The mechanisms of air pollution‐induced health effects involve oxidative stress …

Particulate matter air pollution and respiratory impact on humans and animals

C Losacco, A Perillo - Environmental Science and Pollution Research, 2018 - Springer
Air pollution is now fully acknowledged to be a public health problem and a social issue.
Particulate matter (PM) concentration has been linked with several clinical manifestations of …

The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells

VS Grytting, P Chand, M Låg, J Øvrevik… - Particle and Fibre …, 2022 - Springer
Background People are exposed to ambient particulate matter (PM) from multiple sources
simultaneously in both environmental and occupational settings. However, combinatory …

The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses

K Sawyer, S Mundandhara, AJ Ghio… - Journal of Toxicology …, 2009 - Taylor & Francis
Epidemiologic and occupational studies demonstrated that ambient particulate matter (PM)
and diesel exhaust particles (DEP) exert deleterious effects on human cardiopulmonary …

Particulate matter induces tissue oxinflammation: from mechanism to damage

G Valacchi, N Magnani, B Woodby… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Oxidative stress and oxidative damage are central hypothetical mechanisms
for the adverse effects of airborne particulate matter (PM). Activation of inflammatory cells …

Toxicology of ambient particulate matter

D van Berlo, M Hullmann, RPF Schins - Molecular, Clinical and …, 2012 - Springer
It is becoming increasingly clear that inhalation exposure to particulate matter (PM) can lead
to or exacerbate various diseases, which are not limited to the lung but extend to the …