Interleukin‐18 and interferon‐gamma polymorphisms are implicated on proviral load and susceptibility to human T‐lymphotropic virus type 1 infection

MC Rocha‐Júnior, R Haddad, DC Cilião Alves… - Tissue …, 2012 - Wiley Online Library
Interleukin‐18 (IL‐18) and interferon‐gamma (IFN‐γ) exert important functions in both innate
and adaptive immune responses against intracellular pathogens and viruses. Previous …

IL17A Polymorphism Is Not Associated with Human T-Lymphotropic Virus 1-Associated Myelopathy/Tropical Spastic Paraparesis

HVPC Neco, VGS Teixeira, ACL Trindade… - Viral …, 2017 - liebertpub.com
The human T-lymphotropic virus 1 (HTLV-1) is the causative agent of HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP). The present study investigated the …

Correlation between polymorphisms at interleukin‐6 but not at interleukin‐10 promoter and the risk of human T lymphotropic virus type I‐associated myelopathy …

SR Gadelha, LC Junior Alcântara… - Journal of medical …, 2008 - Wiley Online Library
HTLV‐1 is the etiologic agent of ATL and HAM/TSP. The majority of HTLV‐1‐infected
individuals remain asymptomatic, indicating that the infection alone is not sufficient to cause …

Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic …

AH Sabouri, M Saito, AL Lloyd, AM Vine… - The Journal of …, 2004 - academic.oup.com
To investigate non-human leukocyte antigen candidate genes that influence the outcome of
human T cell lymphotropic virus (HTLV) type I infection, we analyzed 6 single-nucleotide …

[HTML][HTML] Association of IL-10 gene polymorphisms and human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in North-East of Iran …

A Shirdel, MR Azarpazhooh, M Sahebari… - Iranian Journal of …, 2013 - ncbi.nlm.nih.gov
The underlying mechanisms leading to the development of human T-cell lymphotropic virus
type I (HTLV-I) associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-I …

Development of Tropical Spastic Paraparesis in Human T-Lymphotropic Virus Type 1 Carriers Is Influenced by Interleukin 28B Gene Polymorphisms

A Treviño, M Lopez, E Vispo, A Aguilera… - Clinical Infectious …, 2012 - academic.oup.com
Abstract Interleukin 28B (IL28B) rs12979860 polymorphisms were examined in 41
individuals with human T-lymphotrophic virus type 1 (HTLV-1). The alleles CT/TT were more …

IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers

T Assone, FV Souza, KO Gaester… - PLoS neglected …, 2014 - journals.plos.org
Background The polymorphisms of IL28B have been described as important in the
pathogenesis of infections caused by some viruses. The aim of this research was to evaluate …

High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic virus type 1-infected clones are associated with human T-cell …

OM Espíndola, LC Oliveira, P Ferreira, ACCB Leite… - Intervirology, 2015 - karger.com
Background/Aims: Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that
causes a persistent infection, and only 0.5-5% of infected individuals will develop HTLV-1 …

HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis Is Not Associated with SNP rs12979860 of the IL‐28B Gene

ACR Vallinoto, BB Santana, KSG Sá… - Mediators of …, 2015 - Wiley Online Library
The present study investigated the association between the rs12979860 polymorphism in
the IL‐28B gene and HTLV‐1 infection as well as the development of HTLV‐1‐associated …

Lack of evidence to support the association of a single IL28B genotype SNP rs12979860 with the HTLV-1 clinical outcomes and proviral load

SS Sanabani, Y Nukui, J Pereira, AC da Costa… - BMC infectious …, 2012 - Springer
Abstract Background The Interleukin 28B (IL28B) rs12979860 polymorphisms was recently
reported to be associated with the human T-cell leukemia virus type 1 (HTLV-1) proviral load …