Background GRHL2 has been shown to function in ovarian carcinogenesis. However, the
relationship between GRHL2 and cisplatin (DDP) resistance in serous ovarian cancer (SOC) …

Paclitaxel (PTX) resistance contributes to mortality in epithelial ovarian cancer (EOC).
Aerobic glycolysis is elevated in the tumor environment and may influence resistance to PTX …

Introduction GRHL1 belongs to the family of Grainyhead-like (GRHL). Previous studies have
shown that dysregulation of growth and survival pathways is associated with the GRHL …

Objective To explore the effects of GRP78 suppression on the sensitivity to cisplatin and
elucidate the role and mechanism of GRP78 in ovarian cancer cisplatin resistance. Methods …

Aim This study aimed to explore whether the dysregulation of lnc-small nucleolar RNA host
gene 1 (SNHG1) and miR-216b-5p correlated with chemoresistance and indicated poor …

Hepatocellular carcinoma (HCC) continues to cause severe burden worldwide. The limited
options especially toward HCC with metastasis prompts us to identify novel molecules for …

Previously, we have identified the Grainyhead transcription factor 2 gene (GRHL2) as
notably hypomethylated in high-grade (HG) serous epithelial ovarian tumors, compared with …

RGS10 is an important regulator of cell survival and chemoresistance in ovarian cancer. We
recently showed that RGS10 transcript expression is suppressed during acquired …

Abstract Grainyhead-like 2 (GRHL2) transcription factor is implicated in many types of
cancers. However, the role of GRHL2 in colorectal cancer (CRC) has not been fully …

Background: The prognosis of epithelial ovarian cancer (EOC) is poor, and the present
prognostic predictors of EOC are neither sensitive nor specific. Objective: The aim of this …